product summary
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company name :
MyBioSource
product type :
antibody
product name :
GHRH Antibody
catalog :
MBS9406884
quantity :
0.1 mL
price :
225 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS9406884
products type :
Antibody
products full name :
GHRH Antibody
products short name :
GHRH
products name syn :
GRF; INN; GHRF
other names :
somatoliberin isoform 2 preproprotein; Somatoliberin; somatoliberin; growth hormone releasing hormone; Growth hormone-releasing factor; GRF; Growth hormone-releasing hormone; GHRH; Somatocrinin; Somatorelin; INN: Sermorelin
products gene name :
GHRH
other gene names :
GHRH; GHRH; GRF; INN; GHRF; GHRF; GRF; GHRH
uniprot entry name :
SLIB_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
107
specificity :
The antibody detects endogenous level of total GHRH protein.
purity :
Antibodies were purified by affinity purification using immunogen.
form :
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
concentration :
1.0 mg/ml
storage stability :
Store at -20 degree C
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Western blotting: 1:500 - 1:2000. Immunohistochemistry: 1:50 - 1:200
other info1 :
Immunogen Type: Recombinant Protein. Immunogen Description: Recombinant protein of human GHRH.
other info2 :
Target Name: GHRH
products categories :
Total protein Ab
products description :
The protein encoded by this gene belongs to the glucagon family and is a preproprotein that is produced in the hypothalamus. The preproprotein is cleaved to form a 44 aa factor, also called somatocrinin, that acts to stimulate growth hormone release from the pituitary. Variant receptors for somatocrinin have been found in several types of tumors, and antagonists of these receptors can inhibit the growth of the tumors. Defects in this gene are a cause of dwarfism, while hypersecretion of the encoded protein is a cause of gigantism.
ncbi gi num :
296080717
ncbi acc num :
NP_001171660.1
ncbi gb acc num :
NM_001184731.1
uniprot acc num :
P01286
ncbi mol weight :
SDS-PAGE: 12KD
ncbi pathways :
Class B/2 (Secretin Family Receptors) Pathway (1269570); G Alpha (s) Signalling Events Pathway (1269575); GPCR Downstream Signaling Pathway (1269574); GPCR Ligand Binding Pathway (1269544); Glucagon-type Ligand Receptors Pathway (1269572); Signal Transduction Pathway (1269379); Signaling By GPCR Pathway (1269543)
ncbi summary :
The protein encoded by this gene belongs to the glucagon family and is a preproprotein that is produced in the hypothalamus. The preproprotein is cleaved to form a 44 aa factor, also called somatocrinin, that acts to stimulate growth hormone release from the pituitary. Variant receptors for somatocrinin have been found in several types of tumors, and antagonists of these receptors can inhibit the growth of the tumors. Defects in this gene are a cause of dwarfism, while hypersecretion of the encoded protein is a cause of gigantism. [provided by RefSeq, Jul 2008]
uniprot summary :
GHRH: GRF is released by the hypothalamus and acts on the adenohypophyse to stimulate the secretion of growth hormone. Belongs to the glucagon family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 20q11.2. Cellular Component: extracellular space; extracellular region; terminal button. Molecular Function: growth hormone-releasing hormone activity; growth hormone-releasing hormone receptor binding. Biological Process: positive regulation of growth hormone secretion; response to food; positive regulation of insulin-like growth factor receptor signaling pathway; growth hormone secretion; cAMP-mediated signaling; positive regulation of circadian sleep/wake cycle, REM sleep; cell-cell signaling; positive regulation of cAMP biosynthetic process; positive regulation of cell proliferation; adenohypophysis development; positive regulation of multicellular organism growth; G-protein signaling, adenylate cyclase activating pathway
size1 :
0.1 mL
price1 :
225 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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