catalog number :
MBS9406641
products full name :
CD249 Polyclonal Antibody
products short name :
[CD249]
products name syn :
[ENPEP; Glutamyl aminopeptidase; EAP; Aminopeptidase A; AP-A; Differentiation antigen gp160; CD249]
other names :
[glutamyl aminopeptidase; Glutamyl aminopeptidase; glutamyl aminopeptidase; glutamyl aminopeptidase (aminopeptidase A); Aminopeptidase A; AP-A; Differentiation antigen gp160; CD_antigen: CD249]
products gene name :
[CD249]
other gene names :
[ENPEP; ENPEP; APA; CD249; gp160; EAP; AP-A]
uniprot entry name :
AMPE_HUMAN
reactivity :
Human, Mouse, Rat
specificity :
CD249 Polyclonal Antibody detects endogenous levels of CD249 protein.
purity :
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
form :
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
storage stability :
Store at -20 degree C/1 year
tested application :
Western Blot (WB), ELISA (EIA)
app notes :
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
image1 heading :
Western Blot (WB)
other info1 :
Immunogen Type: peptide. Immunogen Description: Synthesized peptide derived from the Internal region of human CD249.
other info2 :
Target Name: CD249
products categories :
Total protein Ab
ncbi acc num :
NP_001968.3
ncbi gb acc num :
NM_001977.3
ncbi mol weight :
SDS-PAGE MW: 110kd
ncbi pathways :
Metabolism Of Angiotensinogen To Angiotensins Pathway (1268749); Metabolism Of Proteins Pathway (1268677); Peptide Hormone Metabolism Pathway (1268746); Renin-angiotensin System Pathway (83075); Renin-angiotensin System Pathway (486)
uniprot summary :
ENPEP: Appears to have a role in the catabolic pathway of the renin-angiotensin system. Probably plays a role in regulating growth and differentiation of early B-lineage cells. Belongs to the peptidase M1 family. Protein type: EC 3.4.11.7; Protease; Membrane protein, integral. Chromosomal Location of Human Ortholog: 4q25. Cellular Component: lysosomal membrane; apical part of cell; integral to plasma membrane; apical plasma membrane; plasma membrane; cytoplasmic vesicle; brush border; external side of plasma membrane. Molecular Function: zinc ion binding; metallopeptidase activity; aminopeptidase activity. Biological Process: cell proliferation; cell migration; cellular protein metabolic process; cell-cell signaling; angiotensin catabolic process in blood; angiogenesis; angiotensin maturation; proteolysis; glomerulus development; regulation of systemic arterial blood pressure by renin-angiotensin