CCL17 Antibody | MyBioSource MBS9406208 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

CCL17 Antibody

catalog :

MBS9406208

quantity :

0.05 mL

price :

200 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, enzyme immunoassay

more info or order :

MyBioSource product webpage

image

image 1 :

Gel: 15%SDS-PAGELane1: Mouse lung tissuelysateLane2: Mouse thymus tissue lysateLane3: Human fetal muscle tissue lysateLysates: 40 ug per lanePrimary antibody: 1/1300 dilutionSecondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilutionExposure time: 45 seconds

image 2 :

The image on the left is immunohistochemistry of paraffin-embedded human colon cancer tissue using 31167(CCL17 Antibody) at dilution 1/70, on the right is treated with the synthetic peptide.

product information

catalog number :

MBS9406208

products type :

Antibody

products full name :

CCL17 Antibody

products short name :

[CCL17]

products name syn :

[chemokine (C-C motif) ligand 17, TARC, ABCD-2, SCYA17, A-152E5.3]

other names :

[C-C motif chemokine 17; C-C motif chemokine 17; C-C motif chemokine 17; chemokine (C-C motif) ligand 17; CC chemokine TARC; Small-inducible cytokine A17; Thymus and activation-regulated chemokine]

products gene name :

[CCL17]

other gene names :

[CCL17; CCL17; TARC; ABCD-2; SCYA17; A-152E5.3; SCYA17; TARC]

uniprot entry name :

CCL17_HUMAN

clonality :

Polyclonal

host :

Rabbit

reactivity :

Human, Mouse

sequence length :

specificity :

The antibody detects endogenous level of total CCL17 protein.

form :

Supplied at 2.6mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, 0.05% sodium azide and 50% glycerol.

storage stability :

Store at -20°C /1 year

tested application :

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

app notes :

ELISA: 1:2000-1:5000. Western blotting: 1:500-1:2000. Immunohistochemistry: 1:100-1:300

image1 heading :

Testing Data

image2 heading :

Immunohistochemistry (IHC)

other info1 :

Immunogen Type: Peptide. Immunogen Description: Synthetic peptide corresponding to a region derived from 73-86 amino acids of human chemokine (C-C motif) ligand 17. Predicted MW: 11 kD

other info2 :

Target Name: CCL17

products categories :

Total protein Ab

products description :

This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells.

ncbi gi num :

4506829

ncbi acc num :

NP_002978.1

ncbi gb acc num :

NM_002987.2

ncbi pathways :

Chemokine Receptors Bind Chemokines Pathway (1269547); Chemokine Signaling Pathway (99051); Chemokine Signaling Pathway (96864); Class A/1 (Rhodopsin-like Receptors) Pathway (1269545); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); GPCR Ligand Binding Pathway (1269544); IL4-mediated Signaling Events Pathway (137933); Peptide Ligand-binding Receptors Pathway (1269546); Signal Transduction Pathway (1269379)

ncbi summary :

This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. [provided by RefSeq, Sep 2014]

uniprot summary :

CCL17: Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. May play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. Binds to CCR4. Belongs to the intercrine beta (chemokine CC) family. Protein type: Secreted, signal peptide; Secreted; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 16q13. Cellular Component: extracellular space; extracellular region. Molecular Function: CCR4 chemokine receptor binding; chemokine activity; receptor binding. Biological Process: G-protein coupled receptor protein signaling pathway; cell-cell signaling; multicellular organismal development; immune response; chemotaxis; inflammatory response; negative regulation of myoblast differentiation

size1 :

0.05 mL

price1 :

200 USD

size2 :

0.1 mL

price2 :

255

more info or order :

MyBioSource product webpage