catalog number :
MBS9405735
products full name :
ETV4 Antibody
products short name :
[ETV4]
products name syn :
[E1AF; PEA3; E1A-F; PEAS3]
other names :
[ETS translocation variant 4 isoform 1; ETS translocation variant 4; ETS translocation variant 4; ets variant 4; Adenovirus E1A enhancer-binding protein; E1A-F; Polyomavirus enhancer activator 3 homolog; Protein PEA3]
products gene name :
[ETV4]
other gene names :
[ETV4; ETV4; E1AF; PEA3; E1A-F; PEAS3; E1AF; PEA3; Protein PEA3]
uniprot entry name :
ETV4_HUMAN
reactivity :
Human, Mouse, Rat
specificity :
The antibody detects endogenous level of total ETV4 protein.
purity :
Antibodies were purified by affinity purification using immunogen.
form :
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
concentration :
1.0 mg/ml
storage stability :
Store at -20°C
tested application :
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
app notes :
Western blotting: 1:500 - 1:2000. Immunohistochemistry: 1:50 - 1:200. Immunofluorescence: 1:50 - 1:200
image1 heading :
Western Blot (WB)
image2 heading :
Immunofluorescence (IF)
other info1 :
Immunogen Type: Recombinant Protein. Immunogen Description: Recombinant protein of human ETV4. SDS-PAGE MW: 53kD
other info2 :
Target Name: ETV4
products categories :
Total protein Ab
products description :
Transcriptional activator that binds to the enhancer of the adenovirus E1A gene; the core-binding sequence is 5'[AC]GGA[AT]GT-3'.
ncbi acc num :
NP_001073143.1
ncbi gb acc num :
NM_001079675.2
ncbi pathways :
LKB1 Signaling Events Pathway (137957); MAPK Family Signaling Cascades Pathway (1269501); MAPK6/MAPK4 Signaling Pathway (1269506); Prostate Cancer Pathway (755440); Signal Transduction Pathway (1269379); Transcriptional Misregulation In Cancer Pathway (523016); Transcriptional Misregulation In Cancer Pathway (522987)
uniprot summary :
ETV4: Transcriptional activator that binds to the enhancer of the adenovirus E1A gene; the core-binding sequence is 5 [AC]GGA[AT]GT-3 . Belongs to the ETS family. Protein type: DNA-binding. Chromosomal Location of Human Ortholog: 17q21. Cellular Component: nucleolus. Molecular Function: protein binding. Biological Process: transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; motor axon guidance; stem cell differentiation; cell differentiation; negative regulation of mammary gland epithelial cell proliferation