product summary
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company name :
MyBioSource
product type :
antibody
product name :
Dynein LC 1 Polyclonal Antibody
catalog :
MBS9405318
quantity :
0.05 mL
price :
200 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
image
image 1 :
MyBioSource MBS9405318 image 1
Western Blot analysis of MCF7 cells using Dynein LC 1 Polyclonal Antibody
product information
catalog number :
MBS9405318
products type :
Antibody
products full name :
Dynein LC 1 Polyclonal Antibody
products short name :
[Dynein LC 1]
products name syn :
[DNAL1; C14orf168; Dynein light chain 1; axonemal]
other names :
[dynein light chain 1, axonemal isoform 2; Dynein light chain 1, axonemal; dynein light chain 1, axonemal; dynein, axonemal, light chain 1]
other gene names :
[DNAL1; DNAL1; CILD16; C14orf168; C14orf168]
uniprot entry name :
DNAL1_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Mouse
sequence length :
151
specificity :
Dynein LC 1 Polyclonal Antibody detects endogenous levels of Dynein LC 1 protein.
purity :
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
form :
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
concentration :
1 mg/ml
storage stability :
Store at -20°C/ 1 year
tested application :
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
app notes :
Western Blot: 1:500 - 1:2000. Immunohistochemistry: 1:100 - 1:300. ELISA: 1:40000. Not yet tested in other applications.
image1 heading :
Western Blot (WB)
other info1 :
Immunogen Type: peptide. Immunogen Description: Synthesized peptide derived from the Internal region of human Dynein LC 1. SDS-PAGE MW: 22 kd
other info2 :
Target Name: Dynein LC 1
products categories :
Total protein Ab
ncbi gi num :
318984125
ncbi acc num :
NP_001188295.1
ncbi gb acc num :
NM_001201366.1
uniprot acc num :
Q4LDG9
ncbi pathways :
Huntington's Disease Pathway (83100); Huntington's Disease Pathway (512)
ncbi summary :
This gene encodes an axonemal dynein light chain which functions as a component of the outer dynein arms complex. This complex acts as the molecular motor that provides the force to move cilia in an ATP-dependent manner. The encoded protein is expressed in tissues with motile cilia or flagella and may be involved in the movement of sperm flagella. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jan 2011]
uniprot summary :
DNAL1: Defects in DNAL1 are the cause of primary ciliary dyskinesia type 16 (CILD16). A disorder characterized by abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia; reduced fertility is often observed in male patients due to abnormalities of sperm tails. Half of the patients exhibit randomization of left-right body asymmetry and situs inversus, due to dysfunction of monocilia at the embryonic node. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome. Belongs to the dynein light chain LC1-type family. 3 isoforms of the human protein are produced by alternative splicing. Chromosomal Location of Human Ortholog: 14q24.3. Disease: Ciliary Dyskinesia, Primary, 16
size1 :
0.05 mL
price1 :
200 USD
size2 :
0.1 mL
price2 :
255
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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