product summary
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company name :
MyBioSource
product type :
antibody
product name :
SIGLEC15 Antibody
catalog :
MBS9404125
quantity :
0.1 mL
price :
320 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS9404125 image 1
Western blot analysis of SIGLEC15 in Rat kidney tissue lysate with SIGLEC15 antibody at (A) 1 and (B) 2 ug/mL
product information
catalog number :
MBS9404125
products type :
Antibody
products full name :
SIGLEC15 Antibody
products short name :
[SIGLEC15]
products name syn :
[Sialic acid-binding Ig-like lectin 15, Siglec-15, CD33L3, CD33 antigen-like 3, HST1361]
other names :
[sialic acid-binding Ig-like lectin 15; Sialic acid-binding Ig-like lectin 15; sialic acid-binding Ig-like lectin 15; sialic acid binding Ig-like lectin 15; CD33 antigen-like 3]
products gene name :
[SIGLEC15]
other gene names :
[SIGLEC15; SIGLEC15; CD33L3; HsT1361; SIGLEC-15; CD33L3; Siglec-15]
uniprot entry name :
SIG15_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
328
specificity :
SIGLEC15 antibody is predicted to not cross-react with other SIGLEC family members.
purity :
Affinity chromatography purified via peptide column
form :
Supplied in PBS containing 0.02% sodium azide.
storage stability :
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
tested application :
ELISA (EIA), Western Blot (WB)
image1 heading :
Western Blot (WB)
other info1 :
Immunogen Type: Peptide. Immunogen Description: Raised against a 15 amino acid peptide near the amino terminus of human SIGLEC15.
other info2 :
Target Name: SIGLEC15
products categories :
Total protein Ab
products description :
Siglecs are vertebrate cell-surface lectins that recognize sialylated glycans and are involved in many physiological processes, such as glycoprotein turnover, cellular trafficking, and pathogen recognition. Most Siglecs are expressed on cells of the immune system. SIGLEC15 is a type-I transmembrane protein consisting of two immunoglobulin (Ig)-like domains, a transmembrane domain containing a lysine residue, and a short cytoplasmic tail. SIGLEC15 can interact with the activating adaptor molecules DAP12/10. Its activating signaling potential and unique preference for glycan recognition implies that SIGLEC15 may be involved in the immune surveillance of tumors and probably plays a conserved, regulatory role in the immune system of vertebrates.
ncbi gi num :
47106069
ncbi acc num :
NP_998767
ncbi gb acc num :
NM_213602.2
ncbi mol weight :
18,086 Da
ncbi pathways :
DAP12 Interactions Pathway (1269283); Immune System Pathway (1269170); Innate Immune System Pathway (1269203)
uniprot summary :
CD33L3: Binds sialylated glycoproteins. Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 18q12.3. Cellular Component: protein complex; integral to membrane; plasma membrane. Biological Process: regulation of bone resorption; regulation of actin cytoskeleton organization and biogenesis; innate immune response
size1 :
0.1 mL
price1 :
320 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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