catalog number :
MBS9403801
products full name :
SNAP29 Antibody
products short name :
[SNAP29]
products name syn :
[CEDNIK; SNAP-29]
other names :
[synaptosomal-associated protein 29; Synaptosomal-associated protein 29; synaptosomal-associated protein 29; synaptosomal-associated protein, 29kDa; Soluble 29 kDa NSF attachment protein]
products gene name :
[SNAP29]
other gene names :
[SNAP29; SNAP29; CEDNIK; SNAP-29; SNAP-29]
uniprot entry name :
SNP29_HUMAN
specificity :
The antibody detects endogenous levels of total SNAP29 protein.
purity :
Antigen affinity purification.
form :
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
concentration :
1.5 mg/mL
storage stability :
Store at -20°C
tested application :
Immunohistochemistry (IHC)
app notes :
Immunohistochemistry: 1:30-1:150
image1 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen Type: Protein. Immunogen Description: Full length fusion protein
other info2 :
Target Name: SNAP29
products categories :
Total protein Ab
products description :
This gene, a member of the SNAP25 gene family, encodes a protein involved in multiple membrane trafficking steps. Two other members of this gene family, SNAP23 and SNAP25, encode proteins that bind a syntaxin protein and mediate synaptic vesicle membrane docking and fusion to the plasma membrane. The protein encoded by this gene binds tightly to multiple syntaxins and is localized to intracellular membrane structures rather than to the plasma membrane. While the protein is mostly membrane-bound, a significant fraction of it is found free in the cytoplasm. Use of multiple polyadenylation sites has been noted for this gene.
ncbi acc num :
NP_004773.1
ncbi gb acc num :
NM_004782.3
ncbi pathways :
SNARE Interactions In Vesicular Transport Pathway (83057); SNARE Interactions In Vesicular Transport Pathway (467)
ncbi summary :
This gene, a member of the SNAP25 gene family, encodes a protein involved in multiple membrane trafficking steps. Two other members of this gene family, SNAP23 and SNAP25, encode proteins that bind a syntaxin protein and mediate synaptic vesicle membrane docking and fusion to the plasma membrane. The protein encoded by this gene binds tightly to multiple syntaxins and is localized to intracellular membrane structures rather than to the plasma membrane. While the protein is mostly membrane-bound, a significant fraction of it is found free in the cytoplasm. Use of multiple polyadenylation sites has been noted for this gene. [provided by RefSeq, Jul 2008]
uniprot summary :
SNAP29: Involved in multiple membrane trafficking steps. Defects in SNAP29 are the cause of CEDNIK syndrome (CEDNIK). CEDNIK is a neurocutaneous syndrome characterized by cerebral dysgenesis, neuropathy, ichthyosis and palmoplantar keratoderma. Belongs to the SNAP-25 family. Protein type: Vesicle. Chromosomal Location of Human Ortholog: 22q11.21. Cellular Component: SNARE complex; centrosome; neuron projection; cytoplasm; plasma membrane; synapse; cell junction. Molecular Function: SNAP receptor activity; syntaxin binding. Biological Process: synaptic vesicle fusion to presynaptic membrane; protein transport; exocytosis; autophagic vacuole fusion; vesicle targeting; synaptic vesicle priming. Disease: Cerebral Dysgenesis, Neuropathy, Ichthyosis, And Palmoplantar Keratoderma Syndrome