catalog number :
MBS9402851
products full name :
APOBEC3C antibody
products short name :
[APOBEC3C]
products name syn :
[A3C; PBI; ARP5; ARDC2; ARDC4; APOBEC1L; bK150C2.3]
other names :
[DNA dC- dU-editing enzyme APOBEC-3C; DNA dC->dU-editing enzyme APOBEC-3C; DNA dC- dU-editing enzyme APOBEC-3C; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C; APOBEC1-like; Phorbolin I]
products gene name :
[APOBEC3C]
other gene names :
[APOBEC3C; APOBEC3C; A3C; PBI; ARP5; ARDC2; ARDC4; APOBEC1L; bK150C2.3; APOBEC1L; PBI; A3C]
uniprot entry name :
ABC3C_HUMAN
specificity :
The antibody detects endogenous level of total APOBEC3C antibody.
purity :
Antibodies were purified by affinity purification using immunogen.
form :
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
concentration :
1.0 mg/ml
storage stability :
Store at -20 degree C
tested application :
Western Blot (WB), Immunofluorescence (IF)
app notes :
Western blotting: 1:500 - 1:2000. Immunofluorescence: 1:50 - 1:200
image1 heading :
Western Blot (WB)
image2 heading :
Immunofluorescence (IF)
other info1 :
Immunogen Type: Recombinant Protein. Immunogen Description: Recombinant protein of human APOBEC3C.
other info2 :
Target Name: APOBEC3C
products categories :
Total protein Ab
products description :
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control.
ncbi acc num :
NP_055323.2
ncbi gb acc num :
NM_014508.2
ncbi summary :
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. [provided by RefSeq, Jul 2008]
uniprot summary :
APOBEC3C: Host cellular restriction factor that may have antiviral activities against exogenous and endogenous viruses, as well as retrotransposons. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation. Belongs to the cytidine and deoxycytidylate deaminase family. Protein type: Hydrolase; EC 3.5.4.-; RNA-binding. Chromosomal Location of Human Ortholog: 22q13.1. Cellular Component: cytoplasm; nucleus. Molecular Function: protein binding; zinc ion binding; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines. Biological Process: viral reproduction; negative regulation of viral genome replication; innate immune response; cytidine deamination; defense response to virus