product summary
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company name :
MyBioSource
product type :
antibody
product name :
CCR8 Antibody
catalog :
MBS9402430
quantity :
0.05 mL
price :
200 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, enzyme immunoassay
more info or order :
image
image 1 :
Gel: 10%SDS-PAGELane1: Hela cell lysateLane2: K562 cell lysateLysates: 80 ug per lanePrimary antibody: 1/400 dilutionSecondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilutionExposure time: 30 seconds
product information
catalog number :
MBS9402430
products type :
Antibody
products full name :
CCR8 Antibody
products short name :
[CCR8]
products name syn :
[chemokine (C-C motif) receptor 8, CY6, TER1, CCR-8, CKRL1, CDw198, CMKBR8, GPRCY6, CMKBRL2, CC-CKR-8]
other names :
[C-C chemokine receptor type 8; C-C chemokine receptor type 8; C-C chemokine receptor type 8; chemokine (C-C motif) receptor 8; CC chemokine receptor CHEMR1; CMKBRL2; Chemokine receptor-like 1; CKR-L1; GPR-CY6; GPRCY6; TER1; CD_antigen: CDw198]
products gene name :
[CCR8]
other gene names :
[CCR8; CCR8; CY6; TER1; CCR-8; CKRL1; CDw198; CMKBR8; GPRCY6; CMKBRL2; CC-CKR-8; CKRL1; CMKBR8; CMKBRL2; C-C CKR-8; CC-CKR-8; CCR-8; CKR-L1; GPRCY6]
uniprot entry name :
CCR8_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human
sequence length :
355
specificity :
The antibody detects endogenous level of total CCR8 protein.
form :
Supplied at 0.8mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, 0.05% sodium azide and 50% glycerol.
storage stability :
Store at -20°C/1 year
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
ELISA: 1:1000-1:5000. Western blotting: 1:200-1:1000
image1 heading :
Testing Data
other info1 :
Immunogen Type: Peptide. Immunogen Description: Synthetic peptide corresponding to a region derived from 175-191 amino acids of Human C-C chemokine receptor type 8
other info2 :
Target Name: CCR8. Predicted MW: 41kD
products categories :
Total protein Ab
products description :
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region.
ncbi gi num :
4885121
ncbi acc num :
NP_005192
ncbi gb acc num :
NM_005201.3
ncbi pathways :
Chemokine Receptors Bind Chemokines Pathway (1269547); Chemokine Signaling Pathway (99051); Chemokine Signaling Pathway (96864); Class A/1 (Rhodopsin-like Receptors) Pathway (1269545); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); G Alpha (i) Signalling Events Pathway (1269576); GPCR Downstream Signaling Pathway (1269574); GPCR Ligand Binding Pathway (1269544); GPCRs, Class A Rhodopsin-like Pathway (198886)
ncbi summary :
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. [provided by RefSeq, Jul 2008]
uniprot summary :
CCR8: Receptor for the chemokine CCL1/SCYA1/I-309. May regulate monocyte chemotaxis and thymic cell line apoptosis. Alternative coreceptor with CD4 for HIV-1 infection. Belongs to the G-protein coupled receptor 1 family. Protein type: Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 3p22. Cellular Component: integral to plasma membrane; plasma membrane. Molecular Function: C-C chemokine receptor activity; chemokine receptor activity; coreceptor activity. Biological Process: G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; immune response; cell adhesion; chemotaxis
size1 :
0.05 mL
price1 :
200 USD
size2 :
0.1 mL
price2 :
255
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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