catalog number :
MBS9401777
products full name :
FCRL4 Antibody
products short name :
[FCRL4]
other names :
[Fc receptor-like protein 4; Fc receptor-like protein 4; Fc receptor-like protein 4; Fc receptor-like 4; Fc receptor homolog 4; FcRH4; IFGP family protein 2; hIFGP2; Immune receptor translocation-associated protein 1; CD_antigen: CD307d]
products gene name :
[FCRL4]
other gene names :
[FCRL4; FCRL4; FCRH4; IGFP2; IRTA1; CD307d; FCRH4; IFGP2; IRTA1; FcR-like protein 4; FcRL4; FcRH4; hIFGP2]
uniprot entry name :
FCRL4_HUMAN
reactivity :
Human, Rat, Mouse
purity :
Affinity purified
form :
PBS, pH 7.4 with 0.02% sodium azide.
concentration :
1.0 mg/ml
storage stability :
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
ELISA: 1:20000-1:80000. WB: 1:200-1:1000. IHC: 1:100-1:500
image1 heading :
Testing Data
image2 heading :
Testing Data
other info1 :
Immunogen Type: Recombinant Protein. Immunogen Description: Rabbit polyclonal FCRL4 (1) antibody was raised against a recombinate humanFCRL4 protein 22-208aa (BC125173)
other info2 :
Target Name: FCRL4
products categories :
Total protein Ab
ncbi acc num :
NP_112572.1
ncbi gb acc num :
NM_031282.2
ncbi mol weight :
56,636 Da
ncbi summary :
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs. This protein may play a role in the function of memory B-cells in the epithelia. Aberrations in the chromosomal region encoding this gene are associated with non-Hodgkin lymphoma and multiple myeloma. [provided by RefSeq, Apr 2009]
uniprot summary :
FCRL4: May function as an inhibitor of the B-cell receptor signaling. May function in the B-cell-mediated immune response. A chromosomal aberration involving FCRL4 is found in non-Hodgkin lymphoma (NHG). Translocation t(1;1)(p36.3; q21.1-2). A chromosomal aberration involving FCRL4 is found in multiple myeloma (MM). Translocation t(1;14)(q21;q32) that forms a FCRL4-IGHA1 fusion protein. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 1q21. Cellular Component: plasma membrane; integral to membrane. Molecular Function: protein binding. Biological Process: immune system process