catalog number :
MBS9401525
products full name :
FGF9 Antibody
products short name :
[FGF9]
products name syn :
[GAF; FGF-9; SYNS3; HBFG-9; HBGF-9]
other names :
[fibroblast growth factor 9; Fibroblast growth factor 9; fibroblast growth factor 9; fibroblast growth factor 9; Glia-activating factor; GAF; Heparin-binding growth factor 9; HBGF-9]
products gene name :
[FGF9]
other gene names :
[FGF9; FGF9; GAF; FGF-9; SYNS3; HBFG-9; HBGF-9; FGF-9; GAF; HBGF-9]
uniprot entry name :
FGF9_HUMAN
reactivity :
Human, Mouse, Rat
specificity :
The antibody detects endogenous levels of total FGF9 protein.
purity :
Antigen affinity purification.
form :
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
concentration :
1.6 mg/ml
storage stability :
Store at -20 degree C
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Western blotting: 1:500-1:2000. Immunohistochemistry: 1:50-1:200
image1 heading :
Testing Data
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen Type: Recombinant Protein. Immunogen Description: Fusion protein corresponding to a region derived from internal residues of human fibroblast growth factor 9
other info2 :
Target Name: FGF9
products categories :
Total protein Ab
products description :
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured glial cells. In nervous system, this protein is produced mainly by neurons and may be important for glial cell development. Expression of the mouse homolog of this gene was found to be dependent on Sonic hedgehog (Shh) signaling.
ncbi acc num :
NP_002001.1
ncbi gb acc num :
NM_002010.2
ncbi pathways :
ARMS-mediated Activation Pathway (1269471); Activated Point Mutants Of FGFR2 Pathway (1268871); Adaptive Immune System Pathway (1269171); Axon Guidance Pathway (1270303); Constitutive Signaling By Aberrant PI3K In Cancer Pathway (1268880); Cytokine Signaling In Immune System Pathway (1269310); DAP12 Interactions Pathway (1269283); DAP12 Signaling Pathway (1269284); Developmental Biology Pathway (1270302); Disease Pathway (1268854)
ncbi summary :
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured glial cells. In nervous system, this protein is produced mainly by neurons and may be important for glial cell development. Expression of the mouse homolog of this gene was found to be dependent on Sonic hedgehog (Shh) signaling. Mice lacking the homolog gene displayed a male-to-female sex reversal phenotype, which suggested a role in testicular embryogenesis. [provided by RefSeq, Jul 2008]
uniprot summary :
Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors.