product summary
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company name :
MyBioSource
product type :
antibody
product name :
cPLA2 (Phospho-Ser505) Polyclonal Antibody
catalog :
MBS9400993
quantity :
0.05 mL
price :
200 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, enzyme immunoassay
more info or order :
image
image 1 :
Western blot analysis of VEC using p-cPLA2 (S505) antibody.
product information
catalog number :
MBS9400993
products type :
Antibody
products full name :
cPLA2 (Phospho-Ser505) Polyclonal Antibody
products short name :
[cPLA2]
products name syn :
[PLA2G4A; CPLA2; PLA2G4; Cytosolic phospholipase A2; cPLA2; Phospholipase A2 group IVA]
other names :
[cytosolic phospholipase A2 isoform 1; Cytosolic phospholipase A2; cytosolic phospholipase A2; phospholipase A2, group IVA (cytosolic, calcium-dependent); Phospholipase A2 group IVAIncluding the following 2 domains:Phospholipase A2 (EC:3.1.1.4)Alternative name(s):Phosphatidylcholine 2-acylhydrolase]
products gene name :
[cPLA2]
other gene names :
[PLA2G4A; PLA2G4A; cPLA2; PLA2G4; cPLA2-alpha; CPLA2; PLA2G4; cPLA2]
uniprot entry name :
PA24A_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
749
specificity :
Phospho-cPLA2 (S505) Polyclonal Antibody detects endogenous levels of cPLA2 protein only when phosphorylated at S505.
purity :
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
form :
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
concentration :
1 mg/ml
storage stability :
Store at -20 degree C/1 year
tested application :
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
app notes :
Western blotting: 1:500 - 1:2000. Immunohistochemistry: 1:100 - 1:300. Immunofluorescence: 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications
image1 heading :
Western Blot (WB)
other info1 :
Immunogen Type: peptide. Immunogen Description: Synthesized peptide derived from human cPLA2 around the phosphorylation site of S505.
other info2 :
Modification: Phospho. Target Species: Human. Target Name: cPLA2
products categories :
Phospho-specific Ab
ncbi gi num :
23943920
ncbi acc num :
NP_077734.1
ncbi gb acc num :
NM_024420.2
uniprot acc num :
P47712
ncbi mol weight :
110kd
ncbi pathways :
ADP Signalling Through P2Y Purinoceptor 1 Pathway (1269354); AGE/RAGE Pathway (698754); Acyl Chain Remodeling Of CL Pathway (1270071); Acyl Chain Remodelling Of PC Pathway (1270062); Acyl Chain Remodelling Of PE Pathway (1270058); Acyl Chain Remodelling Of PG Pathway (1270069); Acyl Chain Remodelling Of PI Pathway (1270067); Acyl Chain Remodelling Of PS Pathway (1270065); Arachidonic Acid Metabolism Pathway (82991); Arachidonic Acid Metabolism Pathway (1270087)
ncbi summary :
This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
uniprot summary :
Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid. Together with its lysophospholipid activity, it is implicated in the initiation of the inflammatory response.
size1 :
0.05 mL
price1 :
200 USD
size2 :
0.1 mL
price2 :
255
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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