catalog number :
MBS9400843
products full name :
Ki-67 Polyclonal Antibody
products short name :
[Ki-67]
products name syn :
[MKI67; Antigen KI-67]
other names :
[antigen KI-67 isoform 2; Antigen KI-67; antigen KI-67; marker of proliferation Ki-67]
products gene name :
[Ki-67]
other gene names :
[MKI67; MKI67; KIA; MIB-; MIB-1; PPP1R105]
uniprot entry name :
KI67_HUMAN
specificity :
Ki-67 Polyclonal Antibody detects endogenous levels of Ki-67 protein.
purity :
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
form :
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
storage stability :
Store at -20° C/1 year
tested application :
WB, IHC, IF, ELISA.
app notes :
Western Blot: 1:500-2000. Immunohistochemistry: 1/100-1/300. Immunofluorescence: 1/200-1/1000. ELISA: 1/2000
image1 heading :
Western Blot (WB)
other info1 :
Immunogen Type: peptide. Immunogen Description: Synthesized peptide derived from the C-terminal region of human Ki-67.
other info2 :
Target Name: Ki-67
products categories :
Total protein Ab
ncbi acc num :
NP_001139438.1
ncbi gb acc num :
NM_001145966.1
ncbi summary :
This gene encodes a nuclear protein that is associated with and may be necessary for cellular proliferation. Alternatively spliced transcript variants have been described. A related pseudogene exists on chromosome X. [provided by RefSeq, Mar 2009]
uniprot summary :
KI-67: a protein that may be a marker of proliferating cells, involved in chromatin compaction. Its expression is altered in many tumor types including osteosarcomas, histiocytomas, prostate, breast and esophageal cancers. Mutated in colon, cervical and lung cancers. Protein type: Nucleolus; Cell cycle regulation. Chromosomal Location of Human Ortholog: 10q26.2. Cellular Component: membrane; cytoplasm; nucleolus; condensed chromosome; nucleus; chromosome, pericentric region. Molecular Function: protein C-terminus binding; protein binding; ATP binding. Biological Process: meiosis; cell proliferation