product summary
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company name :
MyBioSource
product type :
antibody
product name :
SARM Antibody
catalog :
MBS9400786
quantity :
0.1 mL
price :
320 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, enzyme immunoassay
more info or order :
image
image 1 :
Western blot analysis of SARM in human kidney tissue lysate with SARM antibody at (A) 1 and (B) 2 ug/ml.
product information
catalog number :
MBS9400786
products type :
Antibody
products full name :
SARM Antibody
products short name :
[SARM]
products name syn :
[Sterile alpha and TIR motif containing 1]
other names :
[sterile alpha and TIR motif-containing protein 1; Sterile alpha and TIR motif-containing protein 1; sterile alpha and TIR motif-containing protein 1; sterile alpha and TIR motif containing 1; Sterile alpha and Armadillo repeat protein; Sterile alpha motif domain-containing protein 2; MyD88-5; SAM domain-containing protein 2; Tir-1 homolog]
products gene name :
[SARM]
other gene names :
[SARM1; SARM1; SARM; SAMD2; MyD88-5; KIAA0524; SAMD2; SARM; MyD88-5; SAM domain-containing protein 2]
uniprot entry name :
SARM1_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
724
specificity :
At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. SARM antibody recognize the longest isoform.
purity :
Affinity chromatography purified via peptide column
form :
PBS containing 0.02% sodium azide.
storage stability :
Store at 4 degree C for three months and -20 degree C, stable for up to one year.
tested application :
ELISA (EIA), Western Blot (WB)
image1 heading :
Western Blot (WB)
other info1 :
Immunogen Type: Peptide. Immunogen Description: 16 amino acid peptide near the amino terminus of human SARM.
other info2 :
Target Name: SARM
products categories :
Total protein Ab
ncbi gi num :
154090976
ncbi acc num :
NP_055892
ncbi gb acc num :
NM_015077.3
ncbi pathways :
Activated TLR4 Signalling Pathway (1269236); Activation Of IRF3/IRF7 Mediated By TBK1/IKK Epsilon Pathway (1269222); IKK Complex Recruitment Mediated By RIP1 Pathway (1269223); Immune System Pathway (1269170); Innate Immune System Pathway (1269203); MyD88-independent TLR3/TLR4 Cascade Pathway (1269220); TRAF6 Mediated Induction Of TAK1 Complex Pathway (1269225); TRIF-mediated TLR3/TLR4 Signaling Pathway (1269221); Toll Like Receptor 3 (TLR3) Cascade Pathway (1269219); Toll Like Receptor 4 (TLR4) Cascade Pathway (1269234)
uniprot summary :
SARM1: Involved in innate immnune response. Acts as a negative regulator of TICAM1/TRIF-dependent Toll-like receptor signaling by inhibiting induction of TLR3- and TLR4-dependent genes. Specifically blocks TICAM1/TRIF-dependent transcription-factor activation and gene induction, without affecting the MYD88- dependent pathway or non-TLR signaling. Negative regulator of NF- kappa-B and IRF activation. 2 isoforms of the human protein are produced by alternative splicing. Chromosomal Location of Human Ortholog: 17q11. Cellular Component: microtubule; mitochondrion; axon; cytoplasm; dendrite; extrinsic to mitochondrial outer membrane; synapse; cell junction; cytosol. Biological Process: regulation of apoptosis; regulation of dendrite morphogenesis; MyD88-independent toll-like receptor signaling pathway; response to glucose stimulus; toll-like receptor signaling pathway; innate immune response; toll-like receptor 3 signaling pathway; toll-like receptor 4 signaling pathway
size1 :
0.1 mL
price1 :
320 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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