product summary
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company name :
MyBioSource
product type :
antibody
product name :
MICU1 Monoclonal Antibody
catalog :
MBS9400198
quantity :
0.05 mL
price :
200 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry
more info or order :
image
image 1 :
Western blot analysis of 1) MCF7, 2) Mouse Brain Tissue, 3) Rat Brain Tissue using MICU1 Monoclonal Antibody.
image 2 :
Immunohistochemical analysis of paraffin-embedded Human Lung Carcinoma using MICU1 Monoclonal Antibody.
product information
catalog number :
MBS9400198
products type :
Antibody
products full name :
MICU1 Monoclonal Antibody
products short name :
[MICU1]
other names :
[calcium uptake protein 1, mitochondrial isoform 2; Calcium uptake protein 1, mitochondrial; calcium uptake protein 1, mitochondrial; mitochondrial calcium uptake 1; Atopy-related autoantigen CALC; ara CALC; Calcium-binding atopy-related autoantigen 1; Allergen: Hom s 4]
products gene name :
[MICU1]
other gene names :
[MICU1; MICU1; CALC; EFHA3; MPXPS; CBARA1; CALC; CBARA1; ara CALC]
uniprot entry name :
MICU1_HUMAN
clonality :
Monoclonal
host :
Mouse
reactivity :
Human, Mouse, Rat
sequence length :
476
specificity :
The antibody detects endogenous MICU1 protein.
purity :
The antibody was affinity-purified from antiserum by affinity-chromatography
form :
PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
concentration :
1 mg/ml
storage stability :
Store at -20°C/1 year.
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Western blotting: 1:1000-2000. Immunohistochemistry: 1:100-200
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen Type: Recombinant Protein. Immunogen Description: Recombinant Protein
other info2 :
Target Name: MICU1
products categories :
Total protein Ab
ncbi gi num :
306922382
ncbi acc num :
NP_001182447.1
ncbi gb acc num :
NM_001195518.1
uniprot acc num :
Q9BPX6
ncbi mol weight :
SDS-PAGE MW: 55kd
ncbi summary :
This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2013]
uniprot summary :
MICU1: Key regulator of mitochondrial calcium uptake required for calcium entry into mitochondrion. May act as a calcium sensor via its EF-hand domains, gating the activity of a calcium channel partner. Induces T-helper 1-mediated autoreactivity, which is accompanied by the release of IFNG. Belongs to the MICU1 family. 5 isoforms of the human protein are produced by alternative splicing. Protein type: Mitochondrial; Membrane protein, integral; Calcium-binding. Chromosomal Location of Human Ortholog: 10q22.1. Cellular Component: mitochondrion; mitochondrial inner membrane; mitochondrial intermembrane space; intracellular. Molecular Function: identical protein binding; protein binding; protein heterodimerization activity; calcium ion binding. Biological Process: mitochondrial calcium ion homeostasis; defense response; mitochondrial calcium ion transport; protein homooligomerization; elevation of mitochondrial calcium ion concentration. Disease: Myopathy With Extrapyramidal Signs
size1 :
0.05 mL
price1 :
200 USD
size2 :
0.1 mL
price2 :
255
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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