product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human Growth/differentiation factor 11, GDF11 ELISA Kit
catalog :
MBS939778
quantity :
48-Strip-Wells
price :
510 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS939778
products type :
ELISA Kit
products full name :
Human Growth/differentiation factor 11, GDF11 ELISA Kit
products short name :
growth differentiation factor 11
products name syn :
Human Growth/differentiation factor 11 (GDF11) ELISA kit; BMP-11; BMP11; bone morphogenetic protein 11; growth differentiation factor 11
other names :
growth/differentiation factor 11; Growth/differentiation factor 11; growth/differentiation factor 11; GDF-11; bone morphogenetic protein 11; growth differentiation factor 11; Bone morphogenetic protein 11; BMP-11
products gene name :
GDF11
other gene names :
GDF11; GDF11; BMP11; BMP-11; BMP11; GDF-11; BMP-11
uniprot entry name :
GDF11_HUMAN
reactivity :
Human
sequence length :
407
specificity :
This assay has high sensitivity and excellent specificity for detection of human GDF11. No significant cross-reactivity or interference between human GDF11 and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma, tissue homogenates. Assay Type: Quantitative Sandwich. Sensitivity: Typically less than 7 pg/ml.
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
products description :
Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for GDF11 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any GDF11 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for GDF11 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of GDF11 bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi gi num :
5031613
ncbi acc num :
NP_005802.1
ncbi gb acc num :
NM_005811.3
uniprot acc num :
O95390
ncbi mol weight :
45,091 Da
ncbi summary :
The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice and Xenopus suggest that this protein is involved in mesodermal formation and neurogenesis during embryonic development. [provided by RefSeq, Jul 2008]
uniprot summary :
GDF11: Secreted signal that acts globally to specify positional identity along the anterior/posterior axis during development. Play critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern. Belongs to the TGF-beta family. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 12q13.2. Cellular Component: extracellular space. Molecular Function: growth factor activity; cytokine activity; transforming growth factor beta receptor binding. Biological Process: regulation of apoptosis; negative regulation of cell proliferation; nervous system development; negative regulation of cell differentiation; camera-type eye morphogenesis; spinal cord anterior/posterior patterning; ureteric bud development; regulation of MAPKKK cascade; pancreas development; cell maturation; mesoderm development; palate development; skeletal development; cell development; metanephros development; growth
size1 :
48-Strip-Wells
price1 :
510 USD
size2 :
96-Strip-Wells
price2 :
725
size3 :
5x96-Strip-Wells
price3 :
2565
size4 :
10x96-Strip-Wells
price4 :
4800
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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