catalog number :
MBS939560
products type :
ELISA Kit
products full name :
Mouse growth arrest-specific gene-6, gas-6 ELISA Kit
products short name :
growth arrest-specific 6
products name syn :
Mouse growth arrest-specific gene-6 (gas-6) ELISA Kit; AXLLG; AXSF; DKFZp666G247; FLJ34709; AXL receptor tyrosine kinase ligand; AXL stimulatory factor; Mouse growth arrest-specific gene-6 (gas-6)
other names :
growth arrest-specific protein 6; Growth arrest-specific protein 6; growth arrest-specific protein 6; GAS 6; AXL receptor tyrosine kinase ligand; growth arrest specific 6; AXL receptor tyrosine kinase ligand
products gene name :
GAS6
other gene names :
Gas6; Gas6; Gas-6; GAS-6
uniprot entry name :
GAS6_MOUSE
specificity :
This assay has high sensitivity and excellent specificity for detection of Mouse GAS6. No significant cross-reactivity or interference between Mouse GAS6 and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Range: 31.25pg/ml-2000pg/ml. Detection Wavelength: 450 nm. Sensitivity: 17.086 pg/ml
other info2 :
Sample Volume: 50-100ul. Protein Biological Process 1: Cardiovascular
products description :
Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for gas-6 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any gas-6 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for gas-6 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of gas-6 bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi acc num :
NP_062394.2
ncbi gb acc num :
NM_019521.2
ncbi mol weight :
74,610 Da
ncbi pathways :
Cell Surface Interactions At The Vascular Wall Pathway 575507!!Gamma-carboxylation Of Protein Precursors Pathway 575197!!Gamma-carboxylation, Transport, And Amino-terminal Cleavage Of Proteins Pathway 575196!!Hemostasis Pathway 575479!!Metabolism Of Proteins Pathway 575185!!PTM: Gamma Carboxylation, Hypusine Formation And Arylsulfatase Activation Pathway 575195!!Platelet Activation, Signaling And Aggregation Pathway 575489!!Platelet Degranulation Pathway 575501!!Post-translational Protein Modification Pathway 575194!!Removal Of Aminoterminal Propeptides From Gamma-carboxylated Proteins Pathway 575199
uniprot summary :
Function: Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.1 PublicationManual assertion based on experiment in:Ref.3