catalog number :
MBS9391487
products type :
ELISA Kit
products full name :
Monkey Arginine Vasopressin (AVP) ELISA Kit
products short name :
[Arginine Vasopressin (AVP)]
other names :
[arginine vasopressin, partial; Vasopressin-neurophysin 2-copeptin; vasopressin-neurophysin 2-copeptin; arginine vasopressin; AVP-NPII]
products gene name :
[AVP]
other gene names :
[AVP; AVP; VP; ADH; ARVP; AVRP; AVP-NPII; ARVP; VP]
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 6.25 pg/ml - 200 pg/ml. Sensitivity: 1.0 pg/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of AVP (hereafter termed "analyte") in undiluted original Monkey body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
AAG16747.1
ncbi mol weight :
17,325 Da
ncbi pathways :
Aquaporin-mediated Transport Pathway (1269944); BMAL1:CLOCK,NPAS2 Activates Circadian Gene Expression Pathway (1269872); Circadian Clock Pathway (1269871); Class A/1 (Rhodopsin-like Receptors) Pathway (1269545); Defective AVP Causes Neurohypophyseal Diabetes Insipidus (NDI) Pathway (1309124); Disease Pathway (1268854); Disorders Of Transmembrane Transporters Pathway (1268932); G Alpha (q) Signalling Events Pathway (1269578); G Alpha (s) Signalling Events Pathway (1269575); GPCR Downstream Signaling Pathway (1269574)
ncbi summary :
This gene encodes a member of the vasopressin/oxytocin family and preproprotein that is proteolytically processed to generate multiple protein products. These products include the neuropeptide hormone arginine vasopressin, and two other peptides, neurophysin 2 and copeptin. Arginine vasopressin is a posterior pituitary hormone that is synthesized in the supraoptic nucleus and paraventricular nucleus of the hypothalamus. Along with its carrier protein, neurophysin 2, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis where it is either stored or secreted into the bloodstream. The precursor is thought to be activated while it is being transported along the axon to the posterior pituitary. Arginine vasopressin acts as a growth factor by enhancing pH regulation through acid-base transport systems. It has a direct antidiuretic action on the kidney, and also causes vasoconstriction of the peripheral vessels. This hormone can contract smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. Mutations in this gene cause autosomal dominant neurohypophyseal diabetes insipidus (ADNDI). This gene is present in a gene cluster with the related gene oxytocin on chromosome 20. [provided by RefSeq, Nov 2015]
uniprot summary :
AVP: Neurophysin 2 specifically binds vasopressin. Defects in AVP are the cause of diabetes insipidus, neurohypophyseal (NDI). A disease characterized by persistent thirst, polydipsia and polyuria. Affected individuals are apparently normal at birth, but characteristically develop symptoms of vasopression deficiency during childhood. Belongs to the vasopressin/oxytocin family. Protein type: Hormone; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 20p13. Cellular Component: cytosol; extracellular region. Molecular Function: caspase inhibitor activity; neuropeptide hormone activity; protein kinase activity; receptor binding; signal transducer activity; V1A vasopressin receptor binding. Biological Process: cell-cell signaling; generation of precursor metabolites and energy; negative regulation of apoptosis; negative regulation of caspase activity; positive regulation of peptidyl-serine phosphorylation; renal water homeostasis; signal transduction; sodium-independent organic anion transport; water transport. Disease: Diabetes Insipidus, Neurohypophyseal
size4 :
10x96-Strip-Wells