catalog number :
MBS9389630
products type :
ELISA Kit
products full name :
Rat Lactotransferrin (LTF) ELISA Kit
products short name :
[Lactotransferrin (LTF)]
other names :
[lactotransferrin isoform 1 preproprotein; Lactotransferrin; lactotransferrin; lactotransferrin; Growth-inhibiting protein 12; Talalactoferrin]
products gene name :
[LTF]
other gene names :
[LTF; LTF; LF; HLF2; GIG12; HEL110; GIG12; LF; Lactoferrin; Lfcin-H]
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Porcine Body Fluids And Tissue Homogenates. Assay Type: Quantitative Sandwich. Detection Range: 62.5ug/ml-2000ug/ml. Sensitivity: 10ug/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) are less than 15%. Inter-assay Precision: Inter-assay CV (?) are less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of LTF (hereafter termed "analyte") in undiluted original Porcine body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_002334.2
ncbi gb acc num :
NM_002343.5
ncbi mol weight :
73,161 Da
ncbi pathways :
Amyloids Pathway (366238); Disease Pathway (530764); Latent Infection Of Homo Sapiens With Mycobacterium Tuberculosis Pathway (645267); Mtb Iron Assimilation By Chelation Pathway (645273); Phagosomal Maturation (early Endosomal Stage) Pathway (645268); Response Of Mtb To Phagocytosis Pathway (645269)
ncbi summary :
This gene is a member of the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. The protein is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it an important component of the non-specific immune system. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. Antimicrobial, antiviral, antifungal and antiparasitic activity has been found for this protein and its peptides. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]
uniprot summary :
LTF: Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. Belongs to the transferrin family. 2 isoforms of the human protein are produced by alternative promoter. Protein type: EC 3.4.21.-; Protease; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 3p21.31. Cellular Component: cell surface; cytoplasm; extracellular region; extracellular space; nucleus; protein complex; secretory granule; specific granule. Molecular Function: heparin binding; iron ion binding; protein binding; protein serine/threonine kinase activator activity. Biological Process: activation of NF-kappaB transcription factor; antibacterial humoral response; antifungal humoral response; cell redox homeostasis; cellular protein metabolic process; humoral immune response; innate immune response in mucosa; iron assimilation by chelation and transport; negative regulation of apoptosis; negative regulation of ATPase activity; negative regulation of lipopolysaccharide-mediated signaling pathway; negative regulation of viral genome replication; negative regulation of viral reproduction; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of osteoblast differentiation; positive regulation of osteoblast proliferation; positive regulation of toll-like receptor 4 signaling pathway; regulation of cytokine production; regulation of tumor necrosis factor production; retinal homeostasis
size4 :
10x96-Strip-Wells