product summary
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company name :
MyBioSource
product type :
antibody
product name :
POM121 Antibody
catalog :
MBS9386930
quantity :
0.1 mL
price :
440 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
more info or order :
image
image 1 :
Western Blot analysis POM121 using NIH-3T3 whole cell lysates.
product information
catalog number :
MBS9386930
products type :
Antibody
products full name :
POM121 Antibody
products short name :
[POM121]
products name syn :
[DKFZp586G1822; DKFZp586P2220; FLJ41820; KIAA0618; MGC3792; Nuclear envelope pore membrane protein POM 121; Nuclear envelope pore membrane protein POM 121A; Nuclear pore membrane protein 121 kDa; Nucleoporin Nup121; NUP121; P121A_HUMAN; P145; Pom121; POM121 membrane glycoprotein; POM121A; Pore membrane protein of 121 kDa; POM121 transmembrane nucleoporin B (pseudogene);Putative nuclear envelope pore membrane protein POM 121B;]
other names :
[nuclear envelope pore membrane protein POM 121 isoform 1; Nuclear envelope pore membrane protein POM 121; nuclear envelope pore membrane protein POM 121; POM121 transmembrane nucleoporin; Nuclear envelope pore membrane protein POM 121A; Nucleoporin Nup121; Pore membrane protein of 121 kDa]
products gene name :
[POM121]
other gene names :
[POM121; POM121; P145; POM121A; KIAA0618; NUP121; POM121A]
clonality :
polyclonal
host :
rabbit
reactivity :
Human, Mouse, Rat
sequence length :
999
specificity :
POM121 Antibody detects endogenous levels of total POM121
purity :
Immunogen affinity purified
storage stability :
Store at -20 °C.Stable for 12 months from date of receipt
app notes :
WB 1:1000-3000. ELISA(peptide) 1:20000-1:40000. Optimal dilutions/concentrations should be determined by the end user.
image1 heading :
Western Blot (WB)
other info1 :
Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Immunogen: A synthesized peptide derived from human POM121. Function: Essential component of the nuclear pore complex (NPC). The repeat-containing domain may
be involved in anchoring components of the pore complex to the pore membrane. When over expressed in cells induces the formation of cytoplasmic annulate lamellae (AL).
other info2 :
Predicted MW : 128kDa. Observed MW : 125 kDa
ncbi gi num :
380692334
ncbi acc num :
NP_001244119.1
ncbi gb acc num :
NM_001257190.2
uniprot acc num :
Q96HA1
ncbi pathways :
Antiviral Mechanism By IFN-stimulated Genes Pathway (530760); Cell Cycle Pathway (530733); Cell Cycle, Mitotic Pathway (105765); Cytokine Signaling In Immune System Pathway (366171); Disease Pathway (530764); Export Of Viral Ribonucleoproteins From Nucleus Pathway (106080); Gene Expression Pathway (105937); Glucose Transport Pathway (106200); Glycogen Storage Diseases Pathway (1127581); HIV Infection Pathway (105983)
ncbi summary :
This gene encodes a transmembrane protein that localizes to the inner nuclear membrane and forms a core component of the nuclear pore complex, which mediates transport to and from the nucleus. The encoded protein may anchor this complex to the nuclear envelope. There are multiple related genes and pseudogenes for this gene on chromosomes 5, 7, 15, and 22. Alternatively spliced transcript variants encoding different isoforms have been observed. [provided by RefSeq, Jul 2013]
uniprot summary :
POM121: a single-pass membrane protein that is an essential component of the nuclear pore complex (NPC). The repeat-containing domain may be involved in anchoring components of the pore complex to the pore membrane. When overexpressed in cells induces the formation of cytoplasmic annulate lamellae (AL). Stably associated with the NPC throughout interphase and with the endoplasmic reticulum during metaphase. Contains F-X-F-G repeats. Belongs to the POM121 family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Nucleoporin. Chromosomal Location of Human Ortholog: 7q11.23. Cellular Component: nuclear envelope; nuclear pore. Molecular Function: nuclear localization sequence binding; nucleocytoplasmic transporter activity; protein binding; structural constituent of nuclear pore. Biological Process: mitotic nuclear envelope disassembly; mRNA export from nucleus; protein import into nucleus; protein sumoylation; RNA export from nucleus; RNA-mediated gene silencing; tRNA export from nucleus; viral reproduction; viral transcription
size1 :
0.1 mL
price1 :
440 USD
size2 :
0.2 mL
price2 :
715
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
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