product summary
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company name :
MyBioSource
product type :
antibody
product name :
Phospho-IRAK4 (Thr345/Ser346) Antibody
catalog :
MBS9386779
quantity :
0.1 mL
price :
440 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry
more info or order :
image
image 1 :
Western blot analysis Phospho-IRAK4 (Thr345/Ser346) using293 whole cell lysates
product information
catalog number :
MBS9386779
products type :
Antibody
products full name :
Phospho-IRAK4 (Thr345/Ser346) Antibody
products short name :
[IRAK4]
other names :
[interleukin-1 receptor-associated kinase 4 isoform a; Interleukin-1 receptor-associated kinase 4; interleukin-1 receptor-associated kinase 4; interleukin 1 receptor associated kinase 4; Renal carcinoma antigen NY-REN-64]
products gene name :
[IRAK4]
other gene names :
[IRAK4; IRAK4; IPD1; REN64; IRAK-4; NY-REN-64; IRAK-4]
clonality :
Polyclonal
host :
Rabbit
reactivity :
Rat, Human, Mouse
sequence length :
460
specificity :
p16 INK Ab detects endogenous levels of total p16 INK.
purity :
The Ab is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and nonphospho- peptide affinity columns.
concentration :
1.0mg/ml
storage stability :
Store at -20°C. Stable for 12 months from date of receipt
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB 1:1000-3000. IHC 1:200
image1 heading :
Western blot (WB)
ncbi gi num :
166795295
ncbi acc num :
NP_001107654.1
ncbi gb acc num :
NM_001114182.2
uniprot acc num :
Q9NWZ3
ncbi mol weight :
60 kDa
ncbi pathways :
Activated TLR4 Signalling Pathway (106400); Apoptosis Pathway (83060); Apoptosis Pathway (470); Chagas Disease (American Trypanosomiasis) Pathway (147809); Chagas Disease (American Trypanosomiasis) Pathway (147795); Cytokine Signaling In Immune System Pathway (366171); IL-1 Signaling Pathway (198908); IL1-mediated Signaling Events Pathway (137944); Immune System Pathway (106386); Influenza A Pathway (217173)
ncbi summary :
This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
uniprot summary :
IRAK4: a TKL kinase of the IRAK family. The interleukin-1 receptor-associated kinases are important mediators in the signal transduction of Toll-like receptor and IL1R family members, collectively referred to as TIRs. Protein type: EC 2.7.11.1; IRAK family; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Protein kinase, TKL; TKL group. Chromosomal Location of Human Ortholog: 12q12. Cellular Component: cytoplasm; cytosol; endosome membrane; nucleus; plasma membrane. Molecular Function: protein binding; protein kinase activity; protein serine/threonine kinase activity. Biological Process: innate immune response; MyD88-dependent toll-like receptor signaling pathway; neutrophil mediated immunity; positive regulation of I-kappaB kinase/NF-kappaB cascade; toll-like receptor 9 signaling pathway; toll-like receptor signaling pathway. Disease: Invasive Pneumococcal Disease, Recurrent Isolated, 1; Irak4 Deficiency
size1 :
0.1 mL
price1 :
440 USD
size2 :
0.2 mL
price2 :
715
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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