catalog number :
MBS938631
products type :
ELISA Kit
products full name :
Human Insulin-like growth factor 2 mRNA-binding protein 3, IGF2BP3 ELISA Kit
products short name :
insulin-like growth factor 2 mRNA binding protein 3
products name syn :
Human Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) ELISA kit; CT98; DKFZp686F1078; IMP-3; IMP3; KOC1; VICKZ3; IGF II mRNA binding protein 3; IGF-II mRNA-binding protein 3; KH domain containing protein overexpressed in cancer; cancer/testis antigen 98; insulin-like growth factor 2 mRNA binding protein 3
other names :
insulin-like growth factor 2 mRNA-binding protein 3; Insulin-like growth factor 2 mRNA-binding protein 3; insulin-like growth factor 2 mRNA-binding protein 3; IMP-3; VICKZ family member 3; IGF2 mRNA-binding protein 3; IGF-II mRNA-binding protein 3; insulin-like growth factor 2 mRNA binding protein 3; IGF-II mRNA-binding protein 3; VICKZ family member 3
products gene name :
IGF2BP3
other gene names :
IGF2BP3; IGF2BP3; VICKZ3; RCJMB04_5e15; IGF2 mRNA-binding protein 3; IMP-3
uniprot entry name :
IF2B3_CHICK
specificity :
This assay has high sensitivity and excellent specificity for detection of human IGF2BP3. No significant cross-reactivity or interference between human IGF2BP3 and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma, tissue homogenates, Cell lysates. Assay Type: Sandwich. Detection Range: 37.5 pg/ml -2400 pg/ml. Sensitivity: The minimum detectable dose of human IGF2BP3 is typically less than 9.37 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
products description :
Principle of the assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for IGF2BP3 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any IGF2BP3 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for IGF2BP3 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of IGF2BP3 bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi acc num :
NP_001006359.1
ncbi gb acc num :
NM_001006359.1
ncbi mol weight :
64,373 Da
uniprot summary :
Function: RNA-binding factor that may recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation
size4 :
10x96-Strip-Wells