product summary
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company name :
MyBioSource
product type :
antibody
product name :
CD68 Antibody
catalog :
MBS9384073
quantity :
0.1 mL
price :
440 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry
more info or order :
image
image 1 :
MyBioSource MBS9384073 image 1
Western blot analysis of CD68 using HT-29 whole cell lysates
image 2 :
MyBioSource MBS9384073 image 2
Western blot analysis of CD68 using HT-29 whole cell lysates
product information
catalog number :
MBS9384073
products type :
Antibody
products full name :
CD68 Antibody
products short name :
[CD68]
other names :
[macrosialin isoform B; Macrosialin; macrosialin; CD68 molecule; Gp110; CD_antigen: CD68]
products gene name :
[CD68]
other gene names :
[CD68; CD68; GP110; LAMP4; SCARD1]
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human,Mouse,Rat
sequence length :
327
specificity :
ATF-4 (Phospho-Ser219) Ab detects endogenous levels of total ATF-4 (Phospho-Ser219).
purity :
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (ThermoFisher Scientific).
concentration :
1 mg/ml
storage stability :
Store at -20°C. Stable for 12 months from date of receipt.
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Western Blot (WB)1:1000-3000. Immunohistochemistry (IHC) 1:200
image1 heading :
Western Blot (WB)
image2 heading :
Western Blot (WB)
ncbi gi num :
91199550
ncbi acc num :
NP_001035148.1
ncbi gb acc num :
NM_001040059.1
uniprot acc num :
P34810
ncbi mol weight :
36 kDa
ncbi pathways :
Lysosome Pathway (99052); Lysosome Pathway (96865)
ncbi summary :
This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]
uniprot summary :
CD68: Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells. Belongs to the LAMP family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Cell surface; Membrane protein, integral. Chromosomal Location of Human Ortholog: 17p13.1. Cellular Component: membrane
size1 :
0.1 mL
price1 :
440 USD
size2 :
0.2 mL
price2 :
715
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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