product summary
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company name :
MyBioSource
product type :
antibody
product name :
HSP70 Antibody
catalog :
MBS9383251
quantity :
0.1 mL
price :
440 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, enzyme immunoassay
more info or order :
image
image 1 :
Western Blot analysis using HSP70 mouse mAb against Hela (1) cell lysate.
image 2 :
Immunohistochemical analysis of paraffin embedded human breast cancer using HSP70 mouse mAb with DAB staining.
image 3 :
Imunofluorescence analysis of NIH/3T3 cells using HSP70 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye.
product information
catalog number :
MBS9383251
products type :
Antibody
products full name :
HSP70 Antibody
products short name :
[HSP70]
products gene name :
[HSP70]
clonality :
Monoclonal
host :
Mouse
reactivity :
Human
specificity :
HSP70 anitbody detects endogenous levels of total HSP70.
purity :
Affinity-Chromatography
concentration :
1.0mg/ml
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
app notes :
ELISA: 1/10000, WB: 1/500-1/2000, IHC:1/200-1/1000, ICC: 1/200-1/1000. Important: For Western Blots, incubate membrane with diluted antibody in 5% w/v milk, 1x TBS, 0.1% Tween (R) 20 at 4 degree C with gentle shaking, overnight.
image1 heading :
Western Blot
image2 heading :
Immunohistochemistry
image3 heading :
Imunofluorescence
other info1 :
Immunogen: Purified recombinant fragment human HSP70 expressed in E.coli.
other info2 :
Subcellular Location: Cytoskeleton; Cytosol; Endoplasmic reticulum; Extracellular region or secreted; Mitochondrion; Nucleus. Tissue Specificity: By heat shock. Similarity: The N-terminal nucleotide binding domain (NBD) (also known as the ATPase domain) is responsible for binding and hydrolyzing ATP. The C-terminal substrate-binding domain (SBD) (also known as peptide-binding domain) binds to the client/substrate proteins. The two domains are allosteric ally coupled so that, when ATP is bound to the NBD, the SBD binds relatively weakly to clients. When ADP is bound in the NBD, a conformational change enhances the affinity of the SBD for client proteins. Belongs to the heat shock protein 70 family.
products description :
This intron less gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjunction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.
uniprot acc num :
P0DMV8
ncbi mol weight :
70kDa
ncbi summary :
This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins. [provided by RefSeq, Jul 2008]
size1 :
0.1 mL
price1 :
440 USD
size2 :
0.2 mL
price2 :
715
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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