product summary
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company name :
MyBioSource
product type :
antibody
product name :
ARHGDIA Antibody
catalog :
MBS9382981
quantity :
0.1 mL
price :
440 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunocytochemistry, flow cytometry
more info or order :
image
image 1 :
Western Blot analysis using ARHGDIA mAb against human ARHGDIA recombinant protein.(Expected MW is 48.7 kDa)
product information
catalog number :
MBS9382981
products type :
Antibody
products full name :
ARHGDIA Antibody
products short name :
[ARHGDIA]
other names :
[rho GDP-dissociation inhibitor 1 isoform a; Rho GDP-dissociation inhibitor 1; rho GDP-dissociation inhibitor 1; Rho GDP dissociation inhibitor alpha; Rho-GDI alpha]
products gene name :
[ARHGDIA]
other gene names :
[ARHGDIA; ARHGDIA; GDIA1; NPHS8; RHOGDI; RHOGDI-1; HEL-S-47e; GDIA1; Rho GDI 1]
clonality :
Monoclonal
host :
Mouse
reactivity :
Human, Mouse, Monkey
sequence length :
204
specificity :
ARHGDIA antibody detects endogeneous levels of total ARGHDIA
purity :
Affinity-chromatography
form :
Mouse IgG1 in phosphate buffered saline ( without Mg 2 and Ca 2 , pH 7.4, 150 mM NaCI, 0.02% Sodium azide and 50% Glycerol.
storage stability :
Store at -20°C. Stable for 12 months from date of receipt.
tested application :
ELISA, WB, ICC, FCM
app notes :
ELISA 1/10000. WB 1/500-1/2000. ICC 1/200-1/1000. FCM 1/200-1/400
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: Purified recombinant fragment of human ARHGDIA expressed in E.Coli. Subcellular Location: Cytoskeleton, Cytosol; Extracellular region or secreted. Similarity: Belongs to the Rho GDI family.
products description :
Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.
ncbi gi num :
297374782
ncbi acc num :
NP_001172006.1
ncbi gb acc num :
NM_001185077.2
uniprot acc num :
P52565
ncbi mol weight :
26 kDa
ncbi pathways :
Axonal Growth Inhibition (RHOA Activation) Pathway (106454); Axonal Growth Stimulation Pathway (106453); CDC42 Signaling Events Pathway (137994); Neurotrophin Signaling Pathway (101143); Neurotrophin Signaling Pathway (100064); RAC1 Signaling Pathway (169355); Regulation Of CDC42 Activity Pathway (137990); Regulation Of RAC1 Activity Pathway (169346); Regulation Of RhoA Activity Pathway (138070); Rho GTPase Cycle Pathway (106503)
ncbi summary :
This gene encodes a protein that plays a key role in the regulation of signaling through Rho GTPases. The encoded protein inhibits the disassociation of Rho family members from GDP (guanine diphosphate), thereby maintaining these factors in an inactive state. Activity of this protein is important in a variety of cellular processes, and expression of this gene may be altered in tumors. Mutations in this gene have been found in individuals with nephrotic syndrome, type 8. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
uniprot summary :
RhoGDI alpha: Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Monomer. Forms a heterodimer with RAC1. Interacts with FER. Belongs to the Rho GDI family. Protein type: Apoptosis; Cell adhesion; Cell development/differentiation; G protein regulator, misc.; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 17q25.3. Cellular Component: cytoskeleton; cytosol. Molecular Function: protein binding. Biological Process: cell motility; negative regulation of apoptosis; negative regulation of axonogenesis; negative regulation of cell adhesion; positive regulation of axonogenesis; regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction. Disease: Nephrotic Syndrome, Type 8
size1 :
0.1 mL
price1 :
440 USD
size2 :
0.2 mL
price2 :
715
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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