Human Adenosine deaminase CECR1, CECR1 ELISA Kit | MyBioSource MBS938146 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Adenosine deaminase CECR1, CECR1 ELISA Kit

catalog :

MBS938146

quantity :

48-Strip-Wells

price :

510 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS938146

products type :

ELISA Kit

products full name :

Human Adenosine deaminase CECR1, CECR1 ELISA Kit

products short name :

cat eye syndrome chromosome region, candidate 1

products name syn :

Human Adenosine deaminase CECR1 (CECR1) ELISA kit; ADGF; IDGFL; OTTHUMP00000028854; OTTHUMP00000196142; cat eye syndrome critical region protein 1; cat eye syndrome chromosome region; candidate 1

other names :

adenosine deaminase CECR1 isoform a; Adenosine deaminase CECR1; adenosine deaminase CECR1; adenosine deaminase 2; cat eye syndrome critical region protein 1; cat eye syndrome chromosome region, candidate 1; Cat eye syndrome critical region protein 1

products gene name :

CECR1

other gene names :

CECR1; CECR1; PAN; ADA2; ADGF; IDGFL; SNEDS; ADA2; ADGF; IDGFL

uniprot entry name :

CECR1_HUMAN

reactivity :

Human

sequence length :

511

specificity :

This assay has high sensitivity and excellent specificity for detection of human CECR1. No significant cross-reactivity or interference between human CECR1 and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 0.312 ng/ml -20 ng/ml. Sensitivity: The minimum detectable dose of human CECR1 is typically less than 0.078 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

products description :

. Principle of the assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for CECR1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any CECR1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for CECR1 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of CECR1 bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

532691754

ncbi acc num :

NP_001269154.1

ncbi gb acc num :

NM_001282225.1

uniprot acc num :

Q9NZK5

ncbi mol weight :

58,934 Da

ncbi summary :

This gene encodes a member of a subfamily of the adenosine deaminase protein family. The encoded protein is one of two adenosine deaminases found in humans, which regulate levels of the signaling molecule, adenosine. The encoded protein is secreted from monocytes undergoing differentiation and may regulate cell proliferation and differentiation. This gene may be responsible for some of the phenotypic features associated with cat eye syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

uniprot summary :

CECR1: Adenosine deaminase that may contribute to the degradation of extracellular adenosine, a signaling molecule that controls a variety of cellular responses. Requires elevated adenosine levels for optimal enzyme activity. Binds to cell surfaces via proteoglycans and may play a role in the regulation of cell proliferation and differentiation, independently of its enzyme activity. Belongs to the adenosine and AMP deaminases family. ADGF subfamily. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; EC 3.5.4.4; Hydrolase; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 22q11.2. Cellular Component: extracellular space; cytosol. Molecular Function: adenosine deaminase activity; heparin binding; proteoglycan binding; protein homodimerization activity; growth factor activity; zinc ion binding; adenosine receptor binding. Biological Process: adenosine catabolic process; multicellular organismal development; hypoxanthine salvage; inosine biosynthetic process. Disease: Polyarteritis Nodosa, Childhood-onset; Sneddon Syndrome

size1 :

48-Strip-Wells

price1 :

510 USD

size2 :

96-Strip-Wells

price2 :

725

size3 :

5x96-Strip-Wells

price3 :

2565

size4 :

10x96-Strip-Wells

price4 :

4800

more info or order :

MyBioSource product webpage