catalog number :
MBS937874
products type :
ELISA Kit
products full name :
Mouse IgG receptor FcRn large subunit p51, FCGRT ELISA Kit
products short name :
Fc fragment of IgG, receptor, transporter, alpha
products name syn :
Mouse IgG receptor FcRn large subunit p51 (FCGRT) ELISA kit; FCRN; alpha-chain; FcRn alpha chain; IgG receptor FcRn large subunit p51; immunoglobulin receptor; intestinal; heavy chain; major histocompatibility complex class I-like Fc receptor; neonatal Fc-recepto; Fc fragment of IgG; receptor; transporter; alpha
other names :
IgG receptor FcRn large subunit p51; IgG receptor FcRn large subunit p51; IgG receptor FcRn large subunit p51; neonatal Fc receptor; igG Fc fragment receptor transporter alpha chain; Fc receptor, IgG, alpha chain transporter; IgG Fc fragment receptor transporter alpha chain; Neonatal Fc receptor
products gene name :
FCGRT
other gene names :
Fcgrt; Fcgrt; FcRn; Fcrn; FcRn
uniprot entry name :
FCGRN_MOUSE
specificity :
This assay has high sensitivity and excellent specificity for detection of mouse FCGRT. No significant cross-reactivity or interference between mouse FCGRT and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 23.5 pg/ml -1500 pg/ml. Sensitivity: The minimum detectable dose of mouse FCGRT is typically less than 5.8 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
products description :
Principle of the assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for FCGRT has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any FCGRT present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for FCGRT is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of FCGRT bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi acc num :
NP_034319.2
ncbi gb acc num :
NM_010189.3
ncbi mol weight :
40,093 Da
uniprot summary :
FCGRT: Binds to the Fc region of monomeric immunoglobulins gamma. Mediates the uptake of IgG from milk. Possible role in transfer of immunoglobulin G from mother to fetus. Belongs to the immunoglobulin superfamily. Protein type: Membrane protein, integral; Immunoglobulin superfamily; Receptor, misc. Cellular Component: membrane; integral to membrane; plasma membrane. Molecular Function: IgG binding; beta-2-microglobulin binding; antigen binding; IgG receptor activity. Biological Process: antigen processing and presentation; immune response
size4 :
10x96-Strip-Wells