catalog number :
MBS9377793
products type :
ELISA Kit
products full name :
Plant Cytochrome C (CYT-C) ELISA Kit
products short name :
[Cytochrome C (CYT-C)]
other names :
[cytochrome c; Cytochrome c; cytochrome c; cytochrome c, somatic]
products gene name :
[CYT-C]
other gene names :
[CYCS; CYCS; CYC; HCS; THC4; CYC]
uniprot entry name :
CYC_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Tissue Homogenate and Biological Fluids samples. Assay Type: Quantitative Sandwich. Detection Range: 15.6nmol/L-500nmol/L. Sensitivity: 2.0nmol/L.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of CYTC (hereafter termed this analyte) in undiluted original Plant Tissue Homogenate and Biological Fluids samples.
ncbi acc num :
NP_061820.1
ncbi gb acc num :
NM_018947.5
ncbi mol weight :
11,749 Da
ncbi pathways :
AGE/RAGE Pathway (698754); Activation Of Caspases Through Apoptosome-mediated Cleavage Pathway (1270283); Alzheimer's Disease Pathway (83097); Alzheimer's Disease Pathway (509); Alzheimers Disease Pathway (672448); Amyotrophic Lateral Sclerosis (ALS) Pathway (83099); Amyotrophic Lateral Sclerosis (ALS) Pathway (511); Apoptosis Pathway (198797); Apoptosis Pathway (83060); Apoptosis Pathway (470)
ncbi summary :
This gene encodes a small heme protein that functions as a central component of the electron transport chain in mitochondria. The encoded protein associates with the inner membrane of the mitochondrion where it accepts electrons from cytochrome b and transfers them to the cytochrome oxidase complex. This protein is also involved in initiation of apoptosis. Mutations in this gene are associated with autosomal dominant nonsyndromic thrombocytopenia. Numerous processed pseudogenes of this gene are found throughout the human genome.[provided by RefSeq, Jul 2010]
uniprot summary :
CYCS: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Belongs to the cytochrome c family. Protein type: Mitochondrial; Oxidoreductase; Apoptosis; Protein phosphatase, Ser/Thr (non-receptor). Chromosomal Location of Human Ortholog: 7p15.3. Cellular Component: cytosol; mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrion; nucleus; protein phosphatase type 2A complex. Molecular Function: electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity; heme binding; protein binding; protein serine/threonine phosphatase activity. Biological Process: caspase activation via cytochrome c; cellular respiration; mitochondrial electron transport, cytochrome c to oxygen; mitochondrial electron transport, ubiquinol to cytochrome c; mitochondrion organization and biogenesis; response to reactive oxygen species. Disease: Thrombocytopenia 4
size4 :
10x96-Strip-Wells