product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Mouse R-spondin-3, RSPO3 ELISA Kit
catalog :
MBS937494
quantity :
48-Strip-Wells
price :
510 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS937494
products type :
ELISA Kit
products full name :
Mouse R-spondin-3, RSPO3 ELISA Kit
products short name :
R-spondin 3 homolog (Xenopus laevis)
products name syn :
Mouse R-spondin-3 (RSPO3) ELISA kit; CRISTIN1; FLJ14440; PWTSR; THSD2; R-spondin 3; thrombospondin; type I; domain containing 2; thrombospondin-like; R-spondin 3 homolog (Xenopus laevis)
other names :
R-spondin-3; R-spondin-3; R-spondin-3; cabriolet; cristin 1; cristin-1; nucleopondin; roof plate-specific spondin-3; thrombospondin, type I, domain 2; cysteine-rich and single thrombospondin domain-containing protein 1; R-spondin 3 homolog (Xenopus laevis); Cabriolet; Cysteine-rich and single thrombospondin domain-containing protein 1; Cristin-1; Nucleopondin; Roof plate-specific spondin-3
products gene name :
RSPO3
other gene names :
Rspo3; Rspo3; Thsd2; AW742308; Cristin1; 2810459H04Rik; Cristin-1
uniprot entry name :
RSPO3_MOUSE
reactivity :
Mouse
sequence length :
277
specificity :
This assay has high sensitivity and excellent specificity for detection of mouse RSPO3. No significant cross-reactivity or interference between mouse RSPO3 and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 4.7 pg/ml -300 pg/ml. Sensitivity: 1.17 pg/ml.
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
products description :
Principle of the Assay This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for RSPO3 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any RSPO3 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for RSPO3 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of RSPO3 bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi gi num :
269973856
ncbi acc num :
NP_082627.3
ncbi gb acc num :
NM_028351.3
uniprot acc num :
Q2TJ95
ncbi mol weight :
31,454 Da
uniprot summary :
R-spondin-3: Activator of the beta-catenin signaling cascade, leading to TCF-dependent gene activation. Acts both in the canonical Wnt/beta-catenin-dependent pathway and in non-canonical Wnt signaling pathway, probably by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway. Belongs to the R-spondin family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Cell development/differentiation; Secreted. Cellular Component: extracellular space; extracellular region. Molecular Function: heparin binding; frizzled binding; receptor binding. Biological Process: Wnt receptor signaling pathway; response to stimulus; angiogenesis
size1 :
48-Strip-Wells
price1 :
510 USD
size2 :
96-Strip-Wells
price2 :
725
size3 :
5x96-Strip-Wells
price3 :
2565
size4 :
10x96-Strip-Wells
price4 :
4800
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

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