catalog number :
MBS9373764
products type :
ELISA Kit
products full name :
Plant Glutathione Synthetase (GSS) ELISA Kit
products short name :
[Glutathione Synthetase (GSS)]
other names :
[glutathione synthetase; Glutathione synthetase; glutathione synthetase; glutathione synthetase; Glutathione synthase]
products gene name :
[GSS]
other gene names :
[GSS; GSS; GSHS; HEL-S-64p; HEL-S-88n; GSH synthetase; GSH-S]
uniprot entry name :
GSHB_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Plant Tissue Homogenate and Biological Fluids samples. Assay Type: Quantitative Sandwich. Detection Range: 0.625ng/ml-20ng/ml. Sensitivity: 0.1ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of GSS (hereafter termed this analyte) in undiluted original Plant Tissue Homogenate and Biological Fluids samples.
ncbi acc num :
NP_000169.1
ncbi gb acc num :
NM_000178.3
ncbi mol weight :
40,349 Da
ncbi pathways :
Biological Oxidations Pathway (1270189); Cysteine And Methionine Metabolism Pathway (104488); Cysteine And Methionine Metabolism Pathway (103421); Glutathione Biosynthesis, Glutamate = Glutathione Pathway (413393); Glutathione Biosynthesis, Glutamate = Glutathione Pathway (468307); Glutathione Conjugation Pathway (1270213); Glutathione Metabolism Pathway (82973); Glutathione Metabolism Pathway (198824); Glutathione Metabolism Pathway (343); Glutathione Synthesis And Recycling Pathway (1270214)
ncbi summary :
Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency. [provided by RefSeq, Jul 2008]
uniprot summary :
GSS: Defects in GSS are the cause of glutathione synthetase deficiency (GSS deficiency); also known as 5- oxoprolinuria or pyroglutamic aciduria. It is a severe form characterized by an increased rate of hemolysis and defective function of the central nervous system. Defects in GSS are the cause of glutathione synthetase deficiency of erythrocytes (GLUSYNDE)[MIM:231900]. Glutathione synthetase deficiency of erythrocytes is a mild form causing hemolytic anemia. Belongs to the eukaryotic GSH synthase family. Protein type: Ligase; Other Amino Acids Metabolism - glutathione; EC 6.3.2.3. Chromosomal Location of Human Ortholog: 20q11.2. Cellular Component: cytosol. Molecular Function: ATP binding; glutathione binding; glutathione synthase activity; magnesium ion binding; protein binding; protein homodimerization activity. Biological Process: amino acid metabolic process; glutathione biosynthetic process; nervous system development; response to oxidative stress. Disease: Glutathione Synthetase Deficiency; Glutathione Synthetase Deficiency Of Erythrocytes, Hemolytic Anemia Due To
size4 :
10x96-Strip-Wells