catalog number :
MBS9373484
products type :
ELISA Kit
products full name :
Mouse Reticulon 4 Receptor (RTN4R) ELISA Kit
products short name :
[Reticulon 4 Receptor (RTN4R)]
other names :
[reticulon-4 receptor; Reticulon-4 receptor; reticulon-4 receptor; reticulon 4 receptor; Nogo receptor; NgR; Nogo-66 receptor]
products gene name :
[RTN4R]
other gene names :
[RTN4R; RTN4R; NGR; NOGOR; NOGOR; NgR]
uniprot entry name :
RTN4R_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of RTN4R (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_075380.1
ncbi gb acc num :
NM_023004.5
ncbi mol weight :
50,708 Da
ncbi pathways :
Spinal Cord Injury Pathway (739007); P75(NTR)-mediated Signaling Pathway (138019)
ncbi summary :
This gene encodes the receptor for reticulon 4, oligodendrocyte myelin glycoprotein and myelin-associated glycoprotein. This receptor mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. [provided by RefSeq, Jul 2008]
uniprot summary :
RTN4R: Receptor for RTN4, OMG and MAG. Mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. Acts in conjunction with RTN4 and LIGO1 in regulating neuronal precursor cell motility during cortical development. Belongs to the Nogo receptor family. Protein type: Membrane protein, GPI anchor. Chromosomal Location of Human Ortholog: 22q11.21. Cellular Component: cell soma; cell surface; cytoplasm; endoplasmic reticulum; integral to plasma membrane; neuron projection; plasma membrane. Molecular Function: protein binding; protein kinase inhibitor activity. Biological Process: cytokine and chemokine mediated signaling pathway; negative regulation of axon extension; negative regulation of axonogenesis; negative regulation of JAK-STAT cascade; negative regulation of protein kinase activity; positive regulation of GTPase activity. Disease: Schizophrenia
size4 :
10x96-Strip-Wells