Human A disintegrin and metalloproteinase with thrombospondin motifs 9, ADAMTS9 ELISA Kit | MyBioSource MBS937260 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human A disintegrin and metalloproteinase with thrombospondin motifs 9, ADAMTS9 ELISA Kit

catalog :

MBS937260

quantity :

48-Strip-Wells

price :

510 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS937260

products type :

ELISA Kit

products full name :

Human A disintegrin and metalloproteinase with thrombospondin motifs 9, ADAMTS9 ELISA Kit

products short name :

ADAM metallopeptidase with thrombospondin type 1 motif, 9

products name syn :

Human A disintegrin and metalloproteinase with thrombospondin motifs 9 (ADAMTS9) ELISA kit; FLJ42955; KIAA1312; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif; 9; ADAM metallopeptidase with thrombospondin type 1 motif; 9

other names :

A disintegrin and metalloproteinase with thrombospondin motifs 9 preproprotein; A disintegrin and metalloproteinase with thrombospondin motifs 9; A disintegrin and metalloproteinase with thrombospondin motifs 9; ADAM-TS9; ADAMTS-9; ADAM-TS 9; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 9; ADAM metallopeptidase with thrombospondin type 1 motif, 9

products gene name :

ADAMTS9

other gene names :

ADAMTS9; ADAMTS9; KIAA1312; ADAM-TS 9; ADAM-TS9; ADAMTS-9

uniprot entry name :

ATS9_HUMAN

reactivity :

Human

sequence length :

1935

specificity :

This assay has high sensitivity and excellent specificity for detection of human ADAMTS9. No significant cross-reactivity or interference between human ADAMTS9 and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Samples: Serum, plasma, cell culture supernates, tissue homogenates. Assay Type: Sandwich. Detection Range: 0.78 ng/ml - 50 ng/ml. Sensitivity: The minimum detectable dose of human ADAMTS9 is typically less than 0.195 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

products description :

Principle of the assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for ADAMTS9 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any ADAMTS9 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for ADAMTS9 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of ADAMTS9 bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

33624896

ncbi acc num :

NP_891550.1

ncbi gb acc num :

NM_182920.1

uniprot acc num :

Q9P2N4

ncbi mol weight :

216,491 Da

ncbi summary :

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. Members of the ADAMTS family have been implicated in the cleavage of proteoglycans, the control of organ shape during development, and the inhibition of angiogenesis. This gene is localized to chromosome 3p14.3-p14.2, an area known to be lost in hereditary renal tumors. [provided by RefSeq, Jul 2008]

uniprot summary :

ADAMTS9: Cleaves the large aggregating proteoglycans, aggrecan and versican. 3 isoforms of the human protein are produced by alternative splicing. Protein type: EC 3.4.24.-; Protease; Motility/polarity/chemotaxis; Extracellular matrix; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 3p14.1. Cellular Component: extracellular matrix; extracellular space; proteinaceous extracellular matrix; endoplasmic reticulum. Molecular Function: metallopeptidase activity; zinc ion binding; metalloendopeptidase activity. Biological Process: vesicle-mediated transport; protein transport; positive regulation of melanocyte differentiation; multicellular organismal development; glycoprotein catabolic process; proteolysis

size1 :

48-Strip-Wells

price1 :

510 USD

size2 :

96-Strip-Wells

price2 :

725

size3 :

5x96-Strip-Wells

price3 :

2565

size4 :

10x96-Strip-Wells

price4 :

4800

more info or order :

MyBioSource product webpage