catalog number :
MBS9371997
products type :
ELISA Kit
products full name :
Plant Choline Acetyltransferase (CHAT) ELISA Kit
products short name :
[Choline Acetyltransferase (CHAT)]
other names :
[choline acetyltransferase, partial; Choline O-acetyltransferase; choline O-acetyltransferase; choline O-acetyltransferase]
products gene name :
[CHAT]
other gene names :
[CHAT; CHAT; CMS6; CMS1A; CMS1A2; CHOACTASE; CHOACTase; ChAT; Choline acetylase]
uniprot entry name :
CLAT_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Plant Tissue Homogenate and Biological Fluids samples. Assay Type: Quantitative Sandwich. Detection Range: 0.625ng/ml-20ng/ml. Sensitivity: 0.1ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of CHAT (hereafter termed this analyte) in undiluted original Plant Tissue Homogenate and Biological Fluids samples.
ncbi acc num :
AAC37590.1
ncbi mol weight :
70,394 Da
ncbi pathways :
Acetylcholine Neurotransmitter Release Cycle Pathway (1268773); Acetylcholine Synthesis Pathway (198820); Biogenic Amine Synthesis Pathway (198793); Cholinergic Synapse Pathway (217716); Glycerophospholipid Biosynthesis Pathway (1270054); Glycerophospholipid Metabolism Pathway (82989); Glycerophospholipid Metabolism Pathway (364); Metabolism Pathway (1269956); Metabolism Of Lipids And Lipoproteins Pathway (1270001); Neuronal System Pathway (1268763)
ncbi summary :
This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform. [provided by RefSeq, May 2010]
uniprot summary :
CHAT: an enzyme that catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses. Four alternative splice variants have been described. Protein type: Lipid Metabolism - glycerophospholipid; Acetyltransferase; EC 2.3.1.6. Chromosomal Location of Human Ortholog: 10q11.2. Cellular Component: cytoplasm; cytosol; nucleus. Molecular Function: choline O-acetyltransferase activity. Biological Process: neurotransmitter secretion; phosphatidylcholine biosynthetic process. Disease: Myasthenic Syndrome, Congenital, Associated With Episodic Apnea
size4 :
10x96-Strip-Wells