Plant Epidermal Growth Factor (EGF) ELISA Kit | MyBioSource MBS9371333 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Plant Epidermal Growth Factor (EGF) ELISA Kit

catalog :

MBS9371333

quantity :

48-Strip-Wells

price :

470 USD

product information

catalog number :

MBS9371333

products type :

ELISA Kit

products full name :

Plant Epidermal Growth Factor (EGF) ELISA Kit

products short name :

[Epidermal Growth Factor (EGF)]

other names :

[epidermal growth factor, partial; Pro-epidermal growth factor; pro-epidermal growth factor; epidermal growth factor; Epidermal growth factorAlternative name(s):Urogastrone]

products gene name :

[EGF]

other gene names :

[EGF; EGF; URG; HOMG4; EGF]

uniprot entry name :

EGF_HUMAN

reactivity :

Plant

sequence length :

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Undiluted original Plant Tissue Homogenate and Biological Fluids samples. Assay Type: Sandwich (Quantitative). Detection Range: 31.2pg/ml-1000pg/ml. Sensitivity: 5.0pg/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of EGF (hereafter termed this analyte) in undiluted original Plant Tissue Homogenate and Biological Fluids samples.

ncbi gi num :

374922206

ncbi acc num :

AFA26280.1

ncbi mol weight :

129,746 Da

ncbi pathways :

ARMS-mediated Activation Pathway (1269471); Adaptive Immune System Pathway (1269171); Arf6 Signaling Events Pathway (138034); Axon Guidance Pathway (1270303); Bladder Cancer Pathway (83115); Bladder Cancer Pathway (527); Ceramide Signaling Pathway (138023); Choline Metabolism In Cancer Pathway (1059539); Choline Metabolism In Cancer Pathway (1084232); Constitutive Signaling By Aberrant PI3K In Cancer Pathway (1268880)

ncbi summary :

This gene encodes a member of the epidermal growth factor superfamily. The encoded preproprotein is proteolytically processed to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding with high affinity to the cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]

uniprot summary :

EGF: EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. Defects in EGF are the cause of hypomagnesemia type 4 (HOMG4); also known as renal hypomagnesemia normocalciuric. HOMG4 is a disorder characterized by massive renal hypomagnesemia and normal levels of serum calcium and calcium excretion. Clinical features include seizures, mild-to mederate psychomotor retardation, and brisk tendon reflexes. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Hormone; Ligand, receptor tyrosine kinase; Membrane protein, integral. Chromosomal Location of Human Ortholog: 4q25. Cellular Component: extracellular region; extracellular space; lysosomal membrane; receptor complex. Molecular Function: epidermal growth factor receptor binding; growth factor activity; phosphatidylinositol-4,5-bisphosphate 3-kinase activity; protein binding; protein-tyrosine kinase activity; Ras guanyl-nucleotide exchange factor activity; transmembrane receptor protein tyrosine kinase activator activity; Wnt receptor activity; Wnt-protein binding. Biological Process: angiogenesis; DNA replication; epidermal growth factor receptor signaling pathway; MAPKKK cascade; negative regulation of epidermal growth factor receptor signaling pathway; negative regulation of secretion; phosphoinositide-mediated signaling; platelet degranulation; positive regulation of cell proliferation; positive regulation of DNA binding; positive regulation of epidermal growth factor receptor activity; positive regulation of MAP kinase activity; positive regulation of mitosis; positive regulation of phosphorylation; positive regulation of receptor internalization; positive regulation of transcription, DNA-dependent; regulation of phosphoinositide 3-kinase cascade; signal transduction; STAT protein nuclear translocation; Wnt receptor signaling pathway through beta-catenin. Disease: Hypomagnesemia 4, Renal

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095