Fish Peroxisomal Acyl-Coenzyme A Oxidase 1 (ACOX1) ELISA Kit | MyBioSource MBS9368998 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Fish Peroxisomal Acyl-Coenzyme A Oxidase 1 (ACOX1) ELISA Kit

catalog :

MBS9368998

quantity :

48-Strip-Wells

price :

470 USD

product information

catalog number :

MBS9368998

products type :

ELISA Kit

products full name :

Fish Peroxisomal Acyl-Coenzyme A Oxidase 1 (ACOX1) ELISA Kit

products short name :

[Peroxisomal Acyl-Coenzyme A Oxidase 1 (ACOX1)]

other names :

[peroxisomal acyl-coenzyme A oxidase 1 isoform b; Peroxisomal acyl-coenzyme A oxidase 1; peroxisomal acyl-coenzyme A oxidase 1; acyl-CoA oxidase 1, palmitoyl; Palmitoyl-CoA oxidase; Straight-chain acyl-CoA oxidase; SCOX]

products gene name :

[ACOX1]

other gene names :

[ACOX1; ACOX1; ACOX; SCOX; PALMCOX; ACOX; AOX; SCOX]

uniprot entry name :

ACOX1_HUMAN

reactivity :

Fish

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Fish Body Fluids And Tissue Homogenates. Assay Type: Quantitative Sandwich. Detection Range: 0.625ng/ml-20ng/ml. Sensitivity: 0.1ng/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of ACO1 (hereafter termed "analyte") in undiluted original Fish body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

30089974

ncbi acc num :

NP_009223.2

ncbi gb acc num :

NM_007292.5

ncbi mol weight :

70,136 Da

ncbi pathways :

(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate Biosynthesis (6-desaturase) Pathway (1318352); Beta-oxidation Of Very Long Chain Fatty Acids Pathway (1270034); Biosynthesis Of Unsaturated Fatty Acids Pathway (83034); Biosynthesis Of Unsaturated Fatty Acids Pathway (429); Fatty Acid Degradation Pathway (82935); Fatty Acid Degradation Pathway (296); Fatty Acid Metabolism Pathway (868084); Fatty Acid Metabolism Pathway (878045); Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (1270010); Metabolic Pathways (132956)

ncbi summary :

The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

uniprot summary :

ACOX1: Catalyzes the desaturation of acyl-CoAs to 2-trans- enoyl-CoAs. Isoform 1 shows highest activity against medium-chain fatty acyl-CoAs and activity decreases with increasing chain length. Isoform 2 is active against a much broader range of substrates and shows activity towards very long-chain acyl-CoAs. Isoform 2 is twice as active as isoform 1 against 16-hydroxy- palmitoyl-CoA and is 25% more active against 1,16-hexadecanodioyl- CoA. Defects in ACOX1 are the cause of adrenoleukodystrophy pseudoneonatal (Pseudo-NALD); also known as peroxisomal acyl-CoA oxidase deficiency. Pseudo-NALD is a peroxisomal single-enzyme disorder. Clinical features include mental retardation, leukodystrophy, seizures, mild hepatomegaly, hearing deficit. Pseudo-NALD is characterized by increased plasma levels of very-long chain fatty cids, due to decreased or absent peroxisome acyl-CoA oxidase activity. Peroxisomes are intact and functioning. Belongs to the acyl-CoA oxidase family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Lipid Metabolism - unsaturated fatty acid biosynthesis; Oxidoreductase; Lipid Metabolism - fatty acid; EC 1.3.3.6; Lipid Metabolism - alpha-linolenic acid. Chromosomal Location of Human Ortholog: 17q25.1. Cellular Component: intracellular membrane-bound organelle; membrane; mitochondrion; nucleolus; nucleoplasm; nucleus; peroxisomal matrix; peroxisomal membrane; peroxisome; plasma membrane. Molecular Function: acyl-CoA binding; acyl-CoA dehydrogenase activity; acyl-CoA oxidase activity; electron carrier activity; FAD binding; palmitoyl-CoA oxidase activity; PDZ domain binding; protein N-terminus binding; receptor binding. Biological Process: cellular lipid metabolic process; fatty acid beta-oxidation using acyl-CoA dehydrogenase; fatty acid beta-oxidation using acyl-CoA oxidase; fatty acid oxidation; generation of precursor metabolites and energy; lipid homeostasis; lipid metabolic process; peroxisome fission; prostaglandin metabolic process; spermatogenesis; unsaturated fatty acid metabolic process; very-long-chain fatty acid metabolic process. Disease: Peroxisomal Acyl-coa Oxidase Deficiency

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095