Human Tumor necrosis factor receptor superfamily member 17, TNFRSF17 ELISA Kit | MyBioSource MBS936842 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Tumor necrosis factor receptor superfamily member 17, TNFRSF17 ELISA Kit

catalog :

MBS936842

quantity :

96-Strip-Wells

price :

915 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS936842

products type :

ELISA Kit

products full name :

Human Tumor necrosis factor receptor superfamily member 17, TNFRSF17 ELISA Kit

products short name :

tumor necrosis factor receptor superfamily, member 17

products name syn :

Human Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) ELISA kit; BCM; BCMA; CD269; B cell maturation antigen; B-cell maturation factor; tumor necrosis factor receptor superfamily; member 17

other names :

tumor necrosis factor receptor superfamily member 17; Tumor necrosis factor receptor superfamily member 17; tumor necrosis factor receptor superfamily member 17; B-cell maturation factor; B cell maturation antigen; B-cell maturation protein; tumor necrosis factor receptor superfamily, member 17; B-cell maturation protein; CD_antigen: CD269

products gene name :

TNFRSF17

other gene names :

TNFRSF17; TNFRSF17; BCM; BCMA; CD269; TNFRSF13A; BCM; BCMA

uniprot entry name :

TNR17_HUMAN

reactivity :

Human

sequence length :

184

specificity :

This assay has high sensitivity and excellent specificity for detection of human TNFRSF17. No significant cross-reactivity or interference between human TNFRSF17 and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 7.8 pg/ml - 500 pg/ml. Sensitivity: The minimum detectable dose of human TNFRSF17 is typically less than 1.95 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

products description :

. Principle of the assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for TNFRSF17 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any TNFRSF17 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for TNFRSF17 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of TNFRSF17 bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

23238192

ncbi acc num :

NP_001183.2

ncbi gb acc num :

NM_001192.2

uniprot acc num :

Q02223

ncbi mol weight :

20,165 Da

ncbi pathways :

Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Intestinal Immune Network For IgA Production Pathway (128760); Intestinal Immune Network For IgA Production Pathway (128670)

ncbi summary :

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008]

uniprot summary :

TNFRSF17: Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. A chromosomal aberration involving TNFRSF17 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with IL2. Protein type: Oncoprotein; Membrane protein, integral; Receptor, misc. Chromosomal Location of Human Ortholog: 16p13.1. Cellular Component: plasma membrane; integral to membrane; endomembrane system. Molecular Function: receptor activity. Biological Process: cell proliferation; immune system process; multicellular organismal development; signal transduction

size1 :

96-Strip-Wells

price1 :

915 USD

size2 :

5x96-Strip-Wells

price2 :

2565

size3 :

10x96-Strip-Wells

price3 :

4800

more info or order :

MyBioSource product webpage