catalog number :
MBS9368355
products type :
ELISA Kit
products full name :
Human Sialidase-3 (NEU3) ELISA Kit
products short name :
[Sialidase-3 (NEU3)]
other names :
[sialidase-3; Sialidase-3; sialidase-3; neuraminidase 3 (membrane sialidase); Ganglioside sialidase; Membrane sialidase; N-acetyl-alpha-neuraminidase 3]
products gene name :
[NEU3]
other gene names :
[NEU3; NEU3; SIAL3]
uniprot entry name :
NEUR3_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Mouse Serum, Plasma Or Tissue Homogenates Samples. Assay Type: Quantitative Sandwich. Detection Range: 0.25ng/ml-8ng/ml. Sensitivity: 0.1ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of NEU3 (hereafter termed "analyte") in undiluted original Mouse serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is not suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_006647.3
ncbi gb acc num :
NM_006656.5
ncbi mol weight :
51,675 Da
ncbi pathways :
Asparagine N-linked Glycosylation Pathway (1268714); Biosynthesis Of The N-glycan Precursor (dolichol Lipid-linked Oligosaccharide, LLO) And Transfer To A Nascent Protein Pathway (1268715); Glycosphingolipid Metabolism Pathway (1270099); Metabolism Pathway (1269956); Metabolism Of Lipids And Lipoproteins Pathway (1270001); Metabolism Of Proteins Pathway (1268677); Other Glycan Degradation Pathway (82976); Other Glycan Degradation Pathway (346); Post-translational Protein Modification Pathway (1268701); Sialic Acid Metabolism Pathway (1268721)
ncbi summary :
This gene product belongs to a family of glycohydrolytic enzymes which remove sialic acid residues from glycoproteins and glycolipids. It is localized in the plasma membrane, and its activity is specific for gangliosides. It may play a role in modulating the ganglioside content of the lipid bilayer. [provided by RefSeq, Jul 2008]
uniprot summary :
NEU3: Plays a role in modulating the ganglioside content of the lipid bilayer at the level of membrane-bound sialyl glycoconjugates. Belongs to the glycosyl hydrolase 33 family. Protein type: Lipid Metabolism - sphingolipid; EC 3.2.1.18; Hydrolase; Glycan Metabolism - other glycan degradation. Chromosomal Location of Human Ortholog: 11q13.5. Cellular Component: cytoplasm; integral to plasma membrane; intracellular membrane-bound organelle; plasma membrane. Molecular Function: alpha-sialidase activity; exo-alpha-sialidase activity. Biological Process: carbohydrate metabolic process; cellular protein metabolic process; dolichol-linked oligosaccharide biosynthetic process; ganglioside catabolic process; glycosphingolipid metabolic process; oligosaccharide catabolic process; post-translational protein modification; protein amino acid N-linked glycosylation via asparagine; sphingolipid metabolic process
size4 :
10x96-Strip-Wells