Human C-type lectin domain family 2 member D, CLEC2D ELISA Kit | MyBioSource MBS936829 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human C-type lectin domain family 2 member D, CLEC2D ELISA Kit

catalog :

MBS936829

quantity :

48-Strip-Wells

price :

510 USD

more info or order :

MyBioSource product webpage

citations: 1

Reference
Chalan P, Bijzet J, Huitema M, Kroesen B, Brouwer E, Boots A. Expression of Lectin-Like Transcript 1, the Ligand for CD161, in Rheumatoid Arthritis. PLoS ONE. 2015;10:e0132436 pubmed publisher

product information

catalog number :

MBS936829

products type :

ELISA Kit

products full name :

Human C-type lectin domain family 2 member D, CLEC2D ELISA Kit

products short name :

C-type lectin domain family 2, member D

products name syn :

Human C-type lectin domain family 2 member D (CLEC2D) ELISA kit; CLAX; LLT1; OCIL; C-type lectin related f; C-type lectin superfamily 2; member D; lectin-like NK cell receptor; lectin-like transcript 1; osteoclast inhibitory lectin; C-type lectin domain family 2; member D

other names :

C-type lectin domain family 2 member D isoform 2; C-type lectin domain family 2 member D; C-type lectin domain family 2 member D; LLT-1; C-type lectin related f; lectin-like transcript 1; lectin-like NK cell receptor; osteoclast inhibitory lectin; C-type lectin superfamily 2, member D; C-type lectin domain family 2, member D; Lectin-like NK cell receptor; Lectin-like transcript 1; LLT-1; Osteoclast inhibitory lectin

products gene name :

CLEC2D

other gene names :

CLEC2D; CLEC2D; CLAX; LLT1; OCIL; CLAX; LLT1; OCIL; LLT-1

uniprot entry name :

CLC2D_HUMAN

reactivity :

Human

sequence length :

194

specificity :

This assay has high sensitivity and excellent specificity for detection of human CLEC2D. No significant cross-reactivity or interference between human CLEC2D and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Samples: Serum, plasma, tissue homogenates, Cell lysates. Assay Type: Sandwich. Detection Range: 31.25 pg/ml -2000 pg/ml. Sensitivity: The minimum detectable dose of human CLEC2D is typically less than 7.81 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

products description :

Principle of the assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for CLEC2D has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any CLEC2D present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for CLEC2D is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of CLEC2D bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

52426782

ncbi acc num :

NP_001004419.1

ncbi gb acc num :

NM_001004419.4

uniprot acc num :

Q9UHP7

ncbi mol weight :

21,849 Da

ncbi summary :

This gene encodes a member of the natural killer cell receptor C-type lectin family. The encoded protein inhibits osteoclast formation and contains a transmembrane domain near the N-terminus as well as the C-type lectin-like extracellular domain. Several alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Oct 2010]

uniprot summary :

CLEC2D: Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis. Inhibits osteoclast formation. Inhibits bone resorption. Modulates the release of interferon- gamma. Binds high molecular weight sulfated glycosaminoglycans. 6 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 12p13. Cellular Component: cell surface; membrane; integral to plasma membrane; endoplasmic reticulum. Molecular Function: transmembrane receptor activity; carbohydrate binding. Biological Process: cell surface receptor linked signal transduction

size1 :

48-Strip-Wells

price1 :

510 USD

size2 :

96-Strip-Wells

price2 :

725

size3 :

5x96-Strip-Wells

price3 :

2565

size4 :

10x96-Strip-Wells

price4 :

4800

more info or order :

MyBioSource product webpage