catalog number :
MBS9366341
products type :
ELISA Kit
products full name :
Mouse Mitogen Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) ELISA Kit
products short name :
[Mitogen Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4)]
other names :
[mitogen-activated protein kinase kinase kinase kinase 4 isoform 2; Mitogen-activated protein kinase kinase kinase kinase 4; mitogen-activated protein kinase kinase kinase kinase 4; mitogen-activated protein kinase kinase kinase kinase 4; HPK/GCK-like kinase HGK; MAPK/ERK kinase kinase kinase 4; MEK kinase kinase 4; MEKKK 4; Nck-interacting kinase]
products gene name :
[MAP4K4]
other gene names :
[Map4k4; Map4k4; HGK; Nik; AU043147; AU045934; AW046177; 9430080K19Rik; Nik; MEK kinase kinase 4; MEKKK 4]
uniprot entry name :
M4K4_MOUSE
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 0.5 ng/ml - 16 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of MAP4K4 (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_032722.2
ncbi gb acc num :
NM_008696.2
ncbi mol weight :
140,602 Da
ncbi pathways :
Insulin Signaling Pathway (198368); MAPK Signaling Pathway (198294); MAPK Signaling Pathway (83245); MAPK Signaling Pathway (456); XPodNet - Protein-protein Interactions In The Podocyte Expanded By STRING Pathway (755427)
uniprot summary :
HGK: a Ser/Thr kinase of the STE20 subfamily. May play a role in the response to environmental stress and cytokines such as TNF-alpha. May interact with the SH3 domain of the adapter proteins Nck. Binds, via its CNH regulatory domain, to the N- terminal region of SPG3A. Upregulated in primary tumors and tumor cell lines. Required for anchorage-independent growth and ras-dependent focus formation in multiple cell lines. 5 isoforms of the human protein are produced by alternative splicing. Protein type: Protein kinase, STE; Kinase, protein; EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); STE group; STE20 family; MSN subfamily. Cellular Component: cytoplasm. Molecular Function: ATP binding; creatine kinase activity; kinase activity; nucleotide binding; protein kinase activity; protein serine/threonine kinase activity; transferase activity. Biological Process: negative regulation of apoptosis; neurite morphogenesis; phosphorylation; protein amino acid phosphorylation; regulation of apoptosis; regulation of JNK cascade; regulation of mitotic cell cycle; response to stress; stress-activated protein kinase signaling pathway
size4 :
10x96-Strip-Wells