catalog number :
MBS9366167
products type :
ELISA Kit
products full name :
Human Solute Carrier Family 22 Member 6 (SLC22A6) ELISA Kit
products short name :
[Solute Carrier Family 22 Member 6 (SLC22A6)]
other names :
[solute carrier family 22 member 6; Solute carrier family 22 member 6; solute carrier family 22 member 6; solute carrier family 22 member 6; Organic anion transporter 1; rOAT1; renal organic anion transporter 1; rROAT1]
products gene name :
[SLC22A6]
other gene names :
[Slc22a6; Slc22a6; Oat1; Paht; Roat1; Orctl1; Oat1; rOAT1; rROAT1]
uniprot entry name :
S22A6_RAT
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. Assay Type: Sandwich (Quantitative). Detection Range: 62.5 pg/ml - 2000 pg/ml. Sensitivity: 10 pg/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of SLC22A6 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_058920.1
ncbi gb acc num :
NM_017224.2
ncbi mol weight :
60,766 Da
ncbi pathways :
Organic Anion Transport Pathway (1333160); Organic Cation/anion/zwitterion Transport Pathway (1333158); SLC-mediated Transmembrane Transport Pathway (1333129); Transmembrane Transport Of Small Molecules Pathway (1333125); Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway (1333145)
ncbi summary :
multispecific organic anion transporter; involved in anion transport in a proximal tubule in the kidney [RGD, Feb 2006]
uniprot summary :
Involved in the renal elimination of endogenous and exogenous organic anions. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the sodium-independent uptake of 2,3-dimercapto-1-propanesulfonic acid (DMPS), 9-(2-phosphonylmethoxyethyl) guanine (PMEG), 9-(2-phosphonylmethoxyethyl) diaminopurine (PMEDAP), ochratoxin (OTA), acyclovir (ACV), 3'-azido-3-'deoxythymidine (AZT), cimetidine (CMD) and edaravone sulfate. Mediates the sodium-independent uptake of p-aminohippurate (PAH), cidofovir, adefovir, 2,4-dichloro-phenoxyacetate (2,4-D), hippurate (HA), indoleacetate (IA), indoxyl sulfate (IS) and 3-carboxy-4-methyl-5-propyl-2-furanpropionate (CMPF). PAH uptake is inhibited by p-chloromercuribenzenesulphonate (PCMBS), diethyl pyrocarbonate (DEPC), indomethacin, sulindac, diclofenac, carprofen, okadaic acid, benzothiazolylcysteine (BTC), S-chlorotrifluoroethylcysteine (CTFC), cysteine S-conjugates S-dichlorovinylcysteine (DCVC), furosemide, steviol, phorbol 12-myristate 13-acetate (PMA), calcium ionophore A23187, benzylpenicillin, bumetamide, losartan, phenol red, urate and alpha-ketoglutarate (). PAH uptake is inhibited by glutarate and probenecid.
size4 :
10x96-Strip-Wells