catalog number :
MBS9364590
products type :
ELISA Kit
products full name :
Human Solute Carrier Family 22 Member 8 (SLC22A8) ELISA Kit
products short name :
[Solute Carrier Family 22 Member 8 (SLC22A8)]
other names :
[solute carrier family 22 member 8; Solute carrier family 22 member 8; solute carrier family 22 member 8; solute carrier family 22 member 8; Organic anion transporter 3; rOat3]
products gene name :
[SLC22A8]
other gene names :
[Slc22a8; Slc22a8; OCT3; Oat3; Roct; Oat3; rOat3]
uniprot entry name :
S22A8_RAT
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. Assay Type: Sandwich (Quantitative). Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of SLC22A8 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_112622.1
ncbi gb acc num :
NM_031332.1
ncbi mol weight :
59,186 Da
ncbi pathways :
Bile Secretion Pathway (193141); Bile Secretion Pathway (193095); Organic Anion Transport Pathway (1333160); Organic Cation/anion/zwitterion Transport Pathway (1333158); SLC-mediated Transmembrane Transport Pathway (1333129); Transmembrane Transport Of Small Molecules Pathway (1333125); Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway (1333145)
ncbi summary :
organic anion transporter; involved in homovanillic acid (HVA), an end metabolite of dopamine, transport [RGD, Feb 2006]
uniprot summary :
SLC22A8: Plays an important role in the excretion/detoxification of endogenous and exogenous organic anions, especially from the brain and kidney. Involved in the transport basolateral of steviol, fexofenadine. Transports benzylpenicillin (PCG), estrone- 3-sulfate (E1S), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), p-amino-hippurate (PAH), acyclovir (ACV) and ochratoxin (OTA). Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Transporter; Transporter, SLC family; Membrane protein, multi-pass; Membrane protein, integral. Cellular Component: basolateral plasma membrane; integral to membrane; integral to plasma membrane. Molecular Function: inorganic anion exchanger activity; organic anion transmembrane transporter activity; protein kinase C binding; quaternary ammonium group transmembrane transporter activity; sodium-independent organic anion transmembrane transporter activity. Biological Process: quaternary ammonium group transport; response to methotrexate; response to toxin; sodium-independent organic anion transport
size4 :
10x96-Strip-Wells