catalog number :
MBS9364427
products type :
ELISA Kit
products full name :
Human Protein Phosphatase 1 Regulatory Subunit 1C (PPP1R1C) ELISA Kit
products short name :
[Protein Phosphatase 1 Regulatory Subunit 1C (PPP1R1C)]
other names :
[protein phosphatase 1 regulatory subunit 1C isoform 2; Protein phosphatase 1 regulatory subunit 1C; protein phosphatase 1 regulatory subunit 1C; protein phosphatase 1 regulatory inhibitor subunit 1C; Inhibitor-5 of protein phosphatase 1; IPP5]
products gene name :
[PPP1R1C]
other gene names :
[PPP1R1C; PPP1R1C; IPP5; IPP5]
uniprot entry name :
PPR1C_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of PPP1R1C (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001074014.1
ncbi gb acc num :
NM_001080545.2
ncbi mol weight :
13,138 Da
ncbi summary :
Protein phosphatase-1 (PP1) is a major serine/threonine phosphatase that regulates a variety of cellular functions. PP1 consists of a catalytic subunit (see PPP1CA; MIM 176875) and regulatory subunits that determine the subcellular localization of PP1 or regulate its function. PPP1R1C belongs to a group of PP1 inhibitory subunits that are themselves regulated by phosphorylation (Wang et al., 2008 [PubMed 18310074]).[supplied by OMIM, Feb 2010]
uniprot summary :
PPP1R1C: Inhibitor of protein-phosphatase 1. Promotes cell growth and cell cycle progress at the G1/S transition. May increase cell susceptibility to TNF-induced apoptosis. Belongs to the protein phosphatase inhibitor 1 family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Motility/polarity/chemotaxis; Protein phosphatase, regulatory subunit. Chromosomal Location of Human Ortholog: 2q31.3. Cellular Component: cytoplasm. Molecular Function: protein phosphatase inhibitor activity; type 1 serine/threonine specific protein phosphatase inhibitor activity. Biological Process: cell cycle; cell division; negative regulation of protein kinase activity; positive regulation of cell growth
size4 :
10x96-Strip-Wells