catalog number :
MBS9364059
products type :
ELISA Kit
products full name :
Mouse Gastrin-Releasing Peptide Receptor (GRPR) ELISA Kit
products short name :
[Gastrin-Releasing Peptide Receptor (GRPR)]
other names :
[gastrin-releasing peptide receptor; Gastrin-releasing peptide receptor; gastrin-releasing peptide receptor; gastrin releasing peptide receptor; GRP-preferring bombesin receptor]
products gene name :
[GRPR]
other gene names :
[GRPR; GRPR; BB2; GRP-R]
uniprot entry name :
GRPR_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Chicken Body Fluids And Tissue Homogenates. Assay Type: Quantitative Sandwich. Detection Range: 31.2ug/ml-1000ug/ml. Sensitivity: 5.0ug/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%)is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of GRP78 (hereafter termed "analyte") in undiluted original Chicken body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_005305.1
ncbi gb acc num :
NM_005314.2
ncbi mol weight :
43,199 Da
ncbi pathways :
Calcium Signaling Pathway (83050); Calcium Signaling Pathway (459); Class A/1 (Rhodopsin-like Receptors) Pathway (1269545); G Alpha (q) Signalling Events Pathway (1269578); GPCR Downstream Signaling Pathway (1269574); GPCR Ligand Binding Pathway (1269544); GPCRs, Class A Rhodopsin-like Pathway (198886); GPCRs, Other Pathway (198765); Gastrin-CREB Signalling Pathway Via PKC And MAPK (1269592); Neuroactive Ligand-receptor Interaction Pathway (83053)
ncbi summary :
Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene. [provided by RefSeq, Jul 2008]
uniprot summary :
GRPR: Receptor for gastrin releasing peptide (GRP). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Protein type: Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1. Chromosomal Location of Human Ortholog: Xp22.2. Cellular Component: integral to plasma membrane; plasma membrane. Molecular Function: peptide receptor activity, G-protein coupled. Biological Process: cell proliferation; G-protein coupled receptor protein signaling pathway; regulation of cell proliferation
size4 :
10x96-Strip-Wells