ELISA/assay

Mouse Follicle Stimulating Hormone Antibody (Anti-FSH) ELISA Kit

MBS9363826

48-Strip-Wells

470 USD

ELISA Kit

Mouse Follicle Stimulating Hormone Antibody (Anti-FSH) ELISA Kit

[Follicle Stimulating Hormone Antibody (Anti-FSH)]

[follicle-stimulating hormone receptor; Follicle-stimulating hormone receptor; follicle-stimulating hormone receptor; follicle stimulating hormone receptor; Follitropin receptor]

[FSH]

[Fshr; Fshr; FSH-R]

FSHR_MOUSE

Mouse

No significant cross-reactivity or interference between this analyte and analogues is observed.

Store all reagents at 2-8 degree C

Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of Anti-FSH (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

242397446

NP_038551.3

NM_013523.3

77,769 Da

Class A/1 (Rhodopsin-like Receptors) Pathway (1324706); G Alpha (s) Signalling Events Pathway (1324736); GPCR Downstream Signaling Pathway (1324735); GPCR Ligand Binding Pathway (1324705); GPCRs, Class A Rhodopsin-like Pathway (198308); Hormone Ligand-binding Receptors Pathway (1324720); Neuroactive Ligand-receptor Interaction Pathway (83250); Neuroactive Ligand-receptor Interaction Pathway (462); Non-odorant GPCRs Pathway (198395); Ovarian Infertility Genes Pathway (198410)

FSHR: Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Defects in FSHR are a cause of ovarian dysgenesis type 1 (ODG1); also known as premature ovarian failure or gonadal dysgenesis XX type or XX gonadal dysgenesis (XXGD) or hereditary hypergonadotropic ovarian failure or hypergonadotropic ovarian dysgenesis with normal karyotype. ODG1 is an autosomal recessive disease characterized by primary amenorrhea, variable development of secondary sex characteristics, and high serum levels of follicle-stimulating hormone (FSH) and luteinizing hormone (LH). Defects in FSHR are a cause of ovarian hyperstimulation syndrome (OHSS). OHSS is a disorder which occurs either spontaneously or most often as an iatrogenic complication of ovarian stimulation treatments for in vitro fertilization. The clinical manifestations vary from abdominal distention and discomfort to potentially life-threatening, massive ovarian enlargement and capillary leak with fluid sequestration. Pathologic features of this syndrome include the presence of multiple serous and hemorrhagic follicular cysts lined by luteinized cells, a condition called hyperreactio luteinalis. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. 3 isoforms of the human protein are produced by alternative splicing. Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass. Cellular Component: cell surface; endosome; integral to membrane; integral to plasma membrane; membrane; plasma membrane. Molecular Function: follicle-stimulating hormone receptor activity; G-protein coupled receptor activity; peptide hormone binding; peptide receptor activity, G-protein coupled; protein-hormone receptor activity; signal transducer activity. Biological Process: adenylate cyclase activation; cellular water homeostasis; follicle-stimulating hormone signaling pathway; G-protein coupled receptor protein signaling pathway; G-protein signaling, adenylate cyclase activating pathway; G-protein signaling, adenylate cyclase inhibiting pathway; G-protein signaling, coupled to cAMP nucleotide second messenger; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); hormone-mediated signaling; locomotory behavior; negative regulation of bone resorption; neurite development; ovarian follicle development; ovulation cycle process; positive regulation of estrogen receptor signaling pathway; positive regulation of phosphoinositide 3-kinase cascade; primary ovarian follicle growth; regulation of chromosome organization and biogenesis; regulation of estrogen receptor signaling pathway; regulation of hormone metabolic process; regulation of MAPKKK cascade; regulation of osteoclast differentiation; regulation of protein amino acid phosphorylation; regulation of systemic arterial blood pressure; Sertoli cell development; Sertoli cell proliferation; signal transduction; sperm chromatin condensation; spermatid development; spermatogenesis; spermatogenesis, exchange of chromosomal proteins; transcytosis; uterus development

48-Strip-Wells

470 USD

96-Strip-Wells

680

5x96-Strip-Wells

3100

10x96-Strip-Wells

6095