This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
ELISA/assay
product name :
Mouse Gephyrin (GPHN) ELISA Kit
catalog :
MBS9363754
quantity :
48-Strip-Wells
price :
470 USD
product information
catalog number :
MBS9363754
products type :
ELISA Kit
products full name :
Mouse Gephyrin (GPHN) ELISA Kit
products short name :
[Gephyrin (GPHN)]
other names :
[gephyrin; Gephyrin; gephyrin; gephyrin; Molybdopterin adenylyltransferase (EC:2.7.7.75); MPT adenylyltransferaseAlternative name(s):Domain G]
products gene name :
[GPHN]
other gene names :
[GPHN; GPHN; GPH; GEPH; HKPX1; GPHRYN; MOCODC; GPH; KIAA1385; MPT adenylyltransferase; MPT Mo-transferase]
uniprot entry name :
GEPH_HUMAN
reactivity :
Mouse
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Human Body Fluids And Tissue Homogenates. Assay Type: Quantitative Sandwich. Detection Range: 3.12ng/ml-100ng/ml. Sensitivity: 1.0ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of GPD1L (hereafter termed "analyte") in undiluted original Human body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi gi num :
8926308
ncbi acc num :
AAF81785.1
ncbi mol weight :
83,448 Da
ncbi pathways :
GABAergic Synapse Pathway (377263); GABAergic Synapse Pathway (377129); Metabolism Pathway (1269956); Metabolism Of Vitamins And Cofactors Pathway (1270144); Metabolism Of Water-soluble Vitamins And Cofactors Pathway (1270145); Molybdenum Cofactor Biosynthesis Pathway (1270157); Molybdenum Cofactor Biosynthesis Pathway (545431); Molybdenum Cofactor Biosynthesis Pathway (545283)
ncbi summary :
This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described; however, the full-length nature of all transcript variants is not currently known. [provided by RefSeq, Jul 2008]
uniprot summary :
gephyrin: Microtubule-associated protein involved in membrane protein-cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules. Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. Homotrimer. Interacts with GABARAP. Inhibited by copper and tungsten. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Adaptor/scaffold; EC 2.10.1.1; EC 2.7.7.75. Chromosomal Location of Human Ortholog: 14q23.3. Cellular Component: cell junction; cytoplasm; cytoskeleton; plasma membrane; postsynaptic membrane. Molecular Function: ATP binding; metal ion binding. Biological Process: establishment of synaptic specificity at neuromuscular junction; Mo-molybdopterin cofactor biosynthetic process; molybdenum incorporation into molybdenum-molybdopterin complex; molybdopterin cofactor biosynthetic process; vitamin metabolic process; water-soluble vitamin metabolic process. Disease: Hyperekplexia, Hereditary 1; Molybdenum Cofactor Deficiency, Complementation Group C
size1 :
48-Strip-Wells
price1 :
470 USD
size2 :
96-Strip-Wells
price2 :
680
size3 :
5x96-Strip-Wells
price3 :
3100
size4 :
10x96-Strip-Wells
price4 :
6095
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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