ELISA/assay

Mouse ATP-Binding Cassette Sub-Family D Member 2 (ABCD2) ELISA Kit

MBS9362056

48-Strip-Wells

470 USD

ELISA Kit

Mouse ATP-Binding Cassette Sub-Family D Member 2 (ABCD2) ELISA Kit

[ATP-Binding Cassette Sub-Family D Member 2 (ABCD2)]

[ATP-binding cassette sub-family D member 2; ATP-binding cassette sub-family D member 2; ATP-binding cassette sub-family D member 2; ATP binding cassette subfamily D member 2; Adrenoleukodystrophy-like 1; Adrenoleukodystrophy-related protein; hALDR]

[ABCD2]

[ABCD2; ABCD2; ALDR; ABC39; ALDL1; ALDRP; hALDR; ALD1; ALDL1; ALDR; ALDRP; hALDR]

ABCD2_HUMAN

Mouse

No significant cross-reactivity or interference between this analyte and analogues is observed.

Store all reagents at 2-8 degree C

Assay Type: Quantitative Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of ABCD2 (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

9945308

NP_005155.1

NM_005164.3

83,233 Da

ABC Transporters Pathway (83035); ABC Transporters Pathway (436); ABC Transporters In Lipid Homeostasis Pathway (1269905); ABC-family Proteins Mediated Transport Pathway (1269904); Nuclear Receptors In Lipid Metabolism And Toxicity Pathway (198887); Peroxisome Pathway (131226); Peroxisome Pathway (131126); Transmembrane Transport Of Small Molecules Pathway (1269903)

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown; however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters. Mutations in this gene have been observed in patients with adrenoleukodystrophy, a severe demyelinating disease. This gene has been identified as a candidate for a modifier gene, accounting for the extreme variation among adrenoleukodystrophy phenotypes. This gene is also a candidate for a complement group of Zellweger syndrome, a genetically heterogeneous disorder of peroxisomal biogenesis. [provided by RefSeq, Jul 2008]

ABCD2: Probable transporter. Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily. Protein type: Membrane protein, integral; Transporter, ABC family; Membrane protein, multi-pass; Transporter. Chromosomal Location of Human Ortholog: 12q12. Cellular Component: cytosol; integral to membrane; intracellular membrane-bound organelle; peroxisomal membrane; peroxisome. Molecular Function: ATP binding; ATPase activity, coupled to transmembrane movement of substances; protein binding; protein homodimerization activity. Biological Process: fatty acid beta-oxidation; positive regulation of fatty acid beta-oxidation; transmembrane transport; very-long-chain fatty acid catabolic process; very-long-chain fatty acid metabolic process

48-Strip-Wells

470 USD

96-Strip-Wells

680

5x96-Strip-Wells

3100

10x96-Strip-Wells

6095