catalog number :
MBS9361533
products type :
ELISA Kit
products full name :
Canine Prostaglandin Reductase 2 (PTGR2) ELISA Kit
products short name :
[Prostaglandin Reductase 2 (PTGR2)]
other names :
[prostaglandin reductase 2; Prostaglandin reductase 2; prostaglandin reductase 2; prostaglandin reductase 2; 15-oxoprostaglandin 13-reductase; Zinc-binding alcohol dehydrogenase domain-containing protein 1]
products gene name :
[PTGR2]
other gene names :
[PTGR2; PTGR2; PGR2; ZADH1; HEL-S-298; ZADH1; PRG-2]
uniprot entry name :
PTGR2_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of PTGR2 (hereafter termed "analyte") in undiluted original Canine body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001139627.1
ncbi gb acc num :
NM_001146155.1
ncbi mol weight :
19,675 Da
ncbi summary :
This gene encodes an enzyme involved in the metabolism of prostaglandins. The encoded protein catalyzes the NADPH-dependent conversion of 15-keto-prostaglandin E2 to 15-keto-13,14-dihydro-prostaglandin E2. This protein may also be involved in regulating activation of the peroxisome proliferator-activated receptor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
uniprot summary :
PTGR2: Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto- PGE2-alpha with highest activity towards 15-keto-PGE2. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation. Belongs to the NADP-dependent oxidoreductase L4BD family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Oxidoreductase; EC 1.3.1.48. Chromosomal Location of Human Ortholog: 14q24.3. Cellular Component: cytoplasm. Molecular Function: 15-oxoprostaglandin 13-oxidase activity; zinc ion binding. Biological Process: prostaglandin metabolic process
size4 :
10x96-Strip-Wells