Human Low affinity immunoglobulin gamma Fc region receptor III-B, FCGR3B ELISA Kit | MyBioSource MBS935927 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Low affinity immunoglobulin gamma Fc region receptor III-B, FCGR3B ELISA Kit

catalog :

MBS935927

quantity :

48-Strip-Wells

price :

510 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS935927

products type :

ELISA Kit

products full name :

Human Low affinity immunoglobulin gamma Fc region receptor III-B, FCGR3B ELISA Kit

products short name :

Fc fragment of IgG, low affinity IIIb, receptor (CD16b)

products name syn :

Human Low affinity immunoglobulin gamma Fc region receptor III-B (FCGR3B) ELISA kit; CD16; CD16b; FCG3; FCGR3; Fc fragment of IgG; low affinity IIIb; receptor for (CD16) ; Fc-gamma receptor IIIb (CD 16) ; low affinity immunoglobulin gamma Fc region receptor III-B; Fc fragment of IgG; low affinity IIIb; receptor (CD16b)

other names :

low affinity immunoglobulin gamma Fc region receptor III-B isoform 2; Low affinity immunoglobulin gamma Fc region receptor III-B; low affinity immunoglobulin gamma Fc region receptor III-B; fc-gamma RIIIb; fc-gamma RIII-beta; igG Fc receptor III-1; Fc-gamma receptor IIIb (CD 16); Fc fragment of IgG, low affinity IIIb, receptor (CD16b); Fc-gamma RIII-beta; Fc-gamma RIII; Fc-gamma RIIIb; FcRIII; FcRIIIb; FcR-10; IgG Fc receptor III-1; CD_antigen: CD16b

products gene name :

FCGR3B

other gene names :

FCGR3B; FCGR3B; CD16; FCG3; CD16b; FCGR3; FCR-10; FCRIII; FCRIIIb; CD16B; FCG3; FCGR3; IGFR3; Fc-gamma RIII; Fc-gamma RIIIb; FcRIII; FcRIIIb

uniprot entry name :

FCG3B_HUMAN

reactivity :

Human

sequence length :

233

specificity :

This assay has high sensitivity and excellent specificity for detection of human FCGR3B. No significant cross-reactivity or interference between human FCGR3B and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 1.56 ng/ml -100 ng/ml. Sensitivity: 0.39 ng/ml

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

products description :

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for FCGR3B has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any FCGR3B present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for FCGR3B is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of FCGR3B bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

132814489

ncbi acc num :

NP_000561.3

ncbi gb acc num :

NM_000570.4

uniprot acc num :

O75015

ncbi mol weight :

26,216 Da

ncbi pathways :

Leishmaniasis Pathway (144181); Leishmaniasis Pathway (144028); Natural Killer Cell Mediated Cytotoxicity Pathway (83079); Natural Killer Cell Mediated Cytotoxicity Pathway (490); Osteoclast Differentiation Pathway (193147); Osteoclast Differentiation Pathway (193096); Phagosome Pathway (153910); Phagosome Pathway (153859); Staphylococcus Aureus Infection Pathway (172846); Staphylococcus Aureus Infection Pathway (171867)

ncbi summary :

The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1. [provided by RefSeq, Aug 2012]

uniprot summary :

Function: Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.

size1 :

48-Strip-Wells

price1 :

510 USD

size2 :

96-Strip-Wells

price2 :

725

size3 :

5x96-Strip-Wells

price3 :

2565

size4 :

10x96-Strip-Wells

price4 :

4800

more info or order :

MyBioSource product webpage