catalog number :
MBS9358093
products type :
ELISA Kit
products full name :
Human Lysophosphatidic Acid Receptor 2 (LPAR2) ELISA Kit
products short name :
[Lysophosphatidic Acid Receptor 2 (LPAR2)]
other names :
[lysophosphatidic acid receptor 2; Lysophosphatidic acid receptor 2; lysophosphatidic acid receptor 2; lysophosphatidic acid receptor 2; Lysophosphatidic acid receptor Edg-4]
products gene name :
[LPAR2]
other gene names :
[LPAR2; LPAR2; EDG4; LPA2; EDG-4; LPA-2; EDG4; LPA2; LPA receptor 2; LPA-2]
uniprot entry name :
LPAR2_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 3.12 ng/ml - 100 ng/ml. Sensitivity: 1.0 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of LPAR2 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_004711.2
ncbi gb acc num :
NM_004720.5
ncbi mol weight :
39,084 Da
ncbi pathways :
Class A/1 (Rhodopsin-like Receptors) Pathway (1269545); G Alpha (i) Signalling Events Pathway (1269576); G Alpha (q) Signalling Events Pathway (1269578); GPCR Downstream Signaling Pathway (1269574); GPCR Ligand Binding Pathway (1269544); Gastrin-CREB Signalling Pathway Via PKC And MAPK (1269592); LPA Receptor Mediated Events Pathway (137928); Lysosphingolipid And LPA Receptors Pathway (1269567); Neuroactive Ligand-receptor Interaction Pathway (83053); Neuroactive Ligand-receptor Interaction Pathway (462)
ncbi summary :
This gene encodes a member of family I of the G protein-coupled receptors, as well as the EDG family of proteins. This protein functions as a lysophosphatidic acid (LPA) receptor and contributes to Ca2+ mobilization, a critical cellular response to LPA in cells, through association with Gi and Gq proteins. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq, Jul 2008]
uniprot summary :
EDG4: Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Plays a key role in phospholipase C-beta (PLC-beta) signaling pathway. Stimulates phospholipase C (PLC) activity in a manner that is independent of RALA activation. Belongs to the G-protein coupled receptor 1 family. Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass. Chromosomal Location of Human Ortholog: 19p12. Cellular Component: cell surface; cytosol; endocytic vesicle; integral to plasma membrane; plasma membrane. Molecular Function: G-protein coupled receptor activity; lipid binding; PDZ domain binding; protein binding. Biological Process: activation of MAPK activity; elevation of cytosolic calcium ion concentration; G-protein coupled receptor protein signaling pathway; phospholipase C activation; positive regulation of Rho protein signal transduction
size4 :
10x96-Strip-Wells