ELISA/assay

Human N-MYC Proto-Oncogene Protein (MYCN) ELISA Kit

MBS9357940

48-Strip-Wells

470 USD

ELISA Kit

Human N-MYC Proto-Oncogene Protein (MYCN) ELISA Kit

[N-MYC Proto-Oncogene Protein (MYCN)]

[N-myc proto-oncogene protein isoform 2; N-myc proto-oncogene protein; N-myc proto-oncogene protein; v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog; Class E basic helix-loop-helix protein 37; bHLHe37]

[MYCN]

[MYCN; MYCN; NMYC; ODED; MODED; N-myc; bHLHe37; BHLHE37; NMYC; bHLHe37]

MYCN_HUMAN

Human

No significant cross-reactivity or interference between this analyte and analogues is observed.

Store all reagents at 2-8 degree C

Samples: Human Body Fluids And Tissue Homogenates. Assay Type: Quantitative Sandwich. Detection Range: 0.625ng/ml-20ng/ml. Sensitivity: 0.1ng/ml.

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of MYCL1 (hereafter termed "analyte") in undiluted original Human body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.

648216291

NP_001280160.1

NM_001293231.1

49,561 Da

Transcriptional Misregulation In Cancer Pathway (523016); Transcriptional Misregulation In Cancer Pathway (522987)

This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]

N-Myc: a proto-oncogenic transcription factor. Plays a role in cell proliferation, apoptosis and in the development of human tumors. Protein type: Oncoprotein; DNA-binding; Transcription factor. Chromosomal Location of Human Ortholog: 2p24.3. Cellular Component: chromatin; nucleus. Molecular Function: DNA binding; protein binding; protein dimerization activity; transcription factor activity. Biological Process: positive regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent. Disease: Feingold Syndrome 1; Tracheoesophageal Fistula With Or Without Esophageal Atresia

48-Strip-Wells

470 USD

96-Strip-Wells

680

5x96-Strip-Wells

3100

10x96-Strip-Wells

6095